Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 5/20 | 0.40 |
| ▸ | CA1 | P00915 | 4/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22290089 | 0.71 | NAAA (0.41) | POLBCA2CA1CA12CA7 | |
| SCHEMBL2029967 | 0.70 | PPARA (0.46) | PPARACA2CA1EPHX1CA12 | |
| SCHEMBL8915607 | 0.68 | GNAI3 (0.41) | POLBEPHX1 | |
| SCHEMBL2361421 | 0.68 | GNAI3 (0.49) | PPARACA2CA1EPHX1CA12 | |
| SCHEMBL19199368 | 0.68 | CYP11B1 (0.38) | POLB | |
| SCHEMBL28869534 | 0.66 | CA1 (0.50) | PPARAPOLBCA2CA1EPHX1 | |
| SCHEMBL293517 | 0.65 | PPARA (0.58) | PPARACA2CA1EPHX1CA12 | |
| SCHEMBL4563383 | 0.65 | PPARA (0.86) | PPARACA2CA1EPHX1CA12 | |
| SCHEMBL2882733 | 0.65 | PPARA (0.62) | PPARACA2CA1EPHX1CA12 | |
| SCHEMBL21361488 | 0.65 | ALDH1A1 (0.49) | PPARAPOLBCA2CA1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499016-A | 2-Oxo-1-[(acylamino)sulfonyl]azetidines | E. R. SQUIBB & SONS, INC. (US) | 1985-02-12 | — | — | US | disclosed |