Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 8/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.35 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11681606 | 0.86 | TSHR (0.34) | TSHRALDH1A1MAPTDNM1NAAA | |
| SCHEMBL18713492 | 0.84 | FAAH (0.48) | TERTGAAKMT2AMEN1TSHR | |
| SCHEMBL4579500 | 0.83 | GAA (0.50) | GAAKMT2AMEN1PAOXALDH1A1 | |
| SCHEMBL21587511 | 0.80 | FAAH (0.48) | TERTGAAKMT2AMEN1TSHR | |
| SCHEMBL13469081 | 0.79 | GAA (0.46) | GAAKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL24626058 | 0.79 | CYP1A2 (0.46) | TERTGAAKMT2AMEN1TSHR | |
| SCHEMBL4579497 | 0.79 | GAA (0.46) | TERTGAAKMT2AMEN1TSHR | |
| SCHEMBL8747854 | 0.78 | CASP2 (0.55) | GAAKMT2AMEN1ALDH1A1DNM1 | |
| SCHEMBL10654398 | 0.77 | DNM1 (0.46) | TERTPAOXMAPTDNM1 | |
| SCHEMBL8165555 | 0.77 | LMNA (0.44) | TERTGAAKMT2AMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0057159-B1 | AZO DYESTUFFS | CIBA-GEIGY AG (CH) | 1985-08-21 | — | — | EP | disclosed |
| EP-0057159-A2 | Azo dyestuffs | CIBA-GEIGY AG (CH) | 1982-08-04 | — | — | EP | disclosed |