Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PTPRB | P23467 | 1/20 | 0.38 |
| ▸ | ACP1 | P24666 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11320576 | 0.87 | MEN1 (0.50) | MEN1KMT2ACCNE1CDK2GSK3B | |
| SCHEMBL11563416 | 0.87 | MEN1 (0.50) | MEN1KMT2ACCNE1CDK2GSK3B | |
| SCHEMBL10617309 | 0.86 | MEN1 (0.48) | MEN1KMT2ACCNE1CDK2GSK3B | |
| SCHEMBL8909308 | 0.81 | MEN1 (0.58) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL19730317 | 0.80 | MEN1 (0.46) | MEN1KMT2ACCNE1CDK2GSK3B | |
| SCHEMBL1412214 | 0.77 | TPSAB1 (0.50) | CCNE1CDK2GSK3BCASP1SMN1; SMN2 | |
| SCHEMBL11042794 | 0.75 | CCNE1 (0.41) | MEN1KMT2ACCNE1CDK2GSK3B | |
| SCHEMBL356447 | 0.75 | CTSK (0.53) | RAB9ACASP1ALDH1A1CTSS | |
| SCHEMBL14366653 | 0.75 | CTSK (0.50) | MEN1KMT2ARAB9ACASP1LMNA | |
| SCHEMBL4432276 | 0.75 | CTSK (0.50) | MEN1KMT2ARAB9ACASP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4424343-A | Preparation of 1-N- ω-amino-α-hydroxyalkanoyl!kanamycin polysilylates and products | BRISTOL MYERS COMPANY (US) | 1984-01-03 | — | — | US | disclosed |
| US-4283528-A | 1-N-aminohydroxyacyl derivatives of gentamicin B | SCHERING CORPORATION (US) | 1981-08-11 | — | — | US | disclosed |