SCHEMBL4432276

SCHEMBL4432276

C[C@H](NC(=O)OCc1ccccc1)C(=O)ON1C(=O)CCC1=O

nearest known ligand 0.59

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CTSK P43235 5/20 0.50
CTSL P07711 1/20 0.50
CTSB P07858 1/20 0.50
CTSS P25774 1/20 0.50
PREP P48147 2/20 0.49
ATM Q13315 1/20 0.49
MEN1 O00255 1/20 0.48
LMNA P02545 1/20 0.48
KMT2A Q03164 1/20 0.48
CYP1A2 P05177 1/20 0.47
ELANE P08246 1/20 0.46
CTRB1 P17538 2/20 0.46
CASP1 P29466 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
RAB9A P51151 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14366653 1.00 CTSK (0.50) CTSKCTSLCTSBCTSSPREP
SCHEMBL10345811 1.00 CTSK (0.50) CTSKCTSLCTSBCTSSPREP
SCHEMBL10354168 0.95 CTSK (0.51) CTSKCTSLCTSBCTSSPREP
SCHEMBL10357140 0.88 CTSB (0.53) CTSKCTSLCTSBCTSSMEN1
SCHEMBL4425151 0.88 CTSB (0.53) CTSKCTSLCTSBCTSSMEN1
SCHEMBL4039888 0.88 CTSB (0.53) CTSKCTSLCTSBCTSSMEN1
SCHEMBL20529553 0.87 CTRB1 (0.48) CTSKCTSLCTSBCTSSATM
SCHEMBL10975944 0.87 ATM (0.46) CTSKCTSLCTSBCTSSATM
SCHEMBL25933042 0.87 CYP3A4 (0.48) CTSKCTSLCTSBCTSSATM
SCHEMBL10975947 0.87 ATM (0.46) CTSKCTSLCTSBCTSSATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113774513-A Preparation method of cashmere blended product with fatigue resistance 江南织造府(宁波)线业有限公司 2021-12-10 CN claimed
EP-3810615-B1 ARGINASE INHIBITORS AND METHODS OF USE MERCK SHARP & DOHME LLC (US) 2026-01-28 EP disclosed
EP-4619037-A1 SMALL MOLECULE-DRUG-CONJUGATES CLEAVABLE IN A TUMOR MICROENVIRONMENT Lerchen, Hans-Georg (DE) 2025-09-24 EP disclosed
US-12173018-B2 Penicillin-binding protein inhibitors VenatoRx Pharmaceuticals, Inc. (US) 2024-12-24 US disclosed
EP-4426729-A1 SPECIFIC CONJUGATION FOR AN ANTIBODY-DRUG CONJUGATE Hangzhou Dac Biotech Co., Ltd. (CN) 2024-09-11 EP disclosed
EP-4426741-A1 BCMA MONOCLONAL ANTIBODY AND THE ANTIBODY-DRUG CONJUGATE Hangzhou DAC Biotech Co., Ltd. (CN) 2024-09-11 EP disclosed
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 EP disclosed
US-12054501-B2 Compositions and methods for inhibiting arginase activity PRECISION PHARMACEUTICALS, INC. (US) 2024-08-06 US disclosed
WO-2024105197-A1 SMALL MOLECULE-DRUG-CONJUGATES CLEAVABLE IN A TUMOR MICROENVIRONMENT VINCERX PHARMA GMBH (DE) 2024-05-23 WO disclosed
US-20240043379-A1 PRODRUGS OF CYTOTOXIC ACTIVE AGENTS HAVING ENZYMATICALLY CLEAVABLE GROUPS BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2024-02-08 US disclosed
EP-0043247-A1 Peptides for use in determining serum thymic factor KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1982-01-06 EP disclosed
US-4264590-A DIPEPTIDE OF A HALOALANINE ABBOTT LABORATORIES (US) 1981-04-28 US disclosed
EP-0020481-A4 ANTIBACTERIAL PEPTIDE. ABBOTT LAB (US) 1981-04-24 EP disclosed
US-4250085-A PHOSPHONATE-CONTAINING OLIGOPEPTIDES, BACTERICIDES HOFFMANN-LA ROCHE INC. (US) 1981-02-10 US disclosed
EP-0020481-A1 ANTIBACTERIAL PEPTIDE ABBOTT LABORATORIES (US) 1981-01-07 EP disclosed
WO-1980000789-A1 ANTIBACTERIAL PEPTIDE ABBOTT LAB (US) 1980-05-01 WO disclosed
US-4187216-A ELASTASE INHIBITORS HOFFMANN-LA ROCHE INC. (US) 1980-02-05 US disclosed
US-4176116-A ELASTASE ENZYME INHIBITORS HOFFMANN-LA ROCHE INC. (US) 1979-11-27 US disclosed
EP-0002822-A1 Phosphorus containing peptide derivatives, their production, intermediates for their production and pharmaceutical compositions containing them F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1979-07-11 EP disclosed
US-4064270-A ANTHELMINTICS BAYER AKTIENGESELLSCHAFT (DT) 1977-12-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12054501-B2 Compositions and methods for inhibiting arginase activity ARG1, ARG2, PRMT3 CTSK 464/4885CTSL 634/4885CTSB 219/4885
US-20240043379-A1 PRODRUGS OF CYTOTOXIC ACTIVE AGENTS HAVING ENZYMATICALLY CLEAVABLE GROUPS BUB1B, KIF5B, TK1 CTSK 378/4885CTSL 357/4885CTSB 245/4885
US-12173018-B2 Penicillin-binding protein inhibitors PEPD, BPGM, EBPL CTSK 2792/4885CTSL 494/4885CTSB 492/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.