Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11041382 | 0.88 | TP53 (0.49) | POLBTP53GAAMAPTALDH1A1 | |
| SCHEMBL11040213 | 0.84 | IDO1 (0.43) | TP53GAAMAPTALDH1A1KMT2A | |
| SCHEMBL11038855 | 0.83 | TP53 (0.63) | POLBTP53GAAALDH1A1KMT2A | |
| SCHEMBL11047507 | 0.82 | MAPT (0.43) | POLBTP53GAAMAPTALDH1A1 | |
| SCHEMBL11039631 | 0.80 | TP53 (0.49) | TP53GAAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL11044738 | 0.80 | TP53 (0.49) | TP53GAAALDH1A1TSHRHPGD | |
| SCHEMBL10984655 | 0.77 | TP53 (0.68) | POLBTP53GAAMAPTALDH1A1 | |
| SCHEMBL11042738 | 0.74 | SMN1; SMN2 (0.49) | TP53GAAMAPTALDH1A1KMT2A | |
| SCHEMBL10976375 | 0.66 | MAPK1 (0.47) | L3MBTL1 | |
| SCHEMBL10983520 | 0.65 | TP53 (0.74) | TP53GAAMAPTALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0073931-B1 | ANILINO-1,2,3-TRIAZOLE DERIVATIVES, MEDICAMENTS CONTAINING THEM, PROCESS FOR PREPARING THEM, AND THEIR USE | BOEHRINGER INGELHEIM KG (DE) | 1985-02-13 | — | — | EP | disclosed |
| EP-0073931-A1 | Anilino-1,2,3-triazole derivatives, medicaments containing them, process for preparing them, and their use | BOEHRINGER INGELHEIM KG (DE) | 1983-03-16 | — | — | EP | disclosed |