Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.39 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 5/20 | 0.38 |
| ▸ | CA2 | P00918 | 5/20 | 0.38 |
| ▸ | CA4 | P22748 | 5/20 | 0.38 |
| ▸ | CA9 | Q16790 | 5/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11038855 | 0.87 | TP53 (0.63) | TP53SMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL11039631 | 0.86 | TP53 (0.49) | TP53SMN1; SMN2SLC5A1SLC5A2GAA | |
| SCHEMBL11041382 | 0.86 | TP53 (0.49) | TP53SMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL11096860 | 0.86 | SMN1; SMN2 (0.55) | TP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL11095871 | 0.85 | TP53 (0.54) | TP53SMN1; SMN2GAAIDO1TDO2 | |
| SCHEMBL11041232 | 0.82 | KMT2A (0.49) | TP53SMN1; SMN2SLC5A1SLC5A2NPC1 | |
| SCHEMBL11040213 | 0.81 | IDO1 (0.43) | TP53SMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL11044671 | 0.80 | POLB (0.49) | TP53SMN1; SMN2GAAHPGDALDH1A1 | |
| SCHEMBL11047507 | 0.79 | MAPT (0.43) | TP53SMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL10985613 | 0.78 | TP53 (0.74) | TP53SMN1; SMN2SLC5A1SLC5A2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0073931-B1 | ANILINO-1,2,3-TRIAZOLE DERIVATIVES, MEDICAMENTS CONTAINING THEM, PROCESS FOR PREPARING THEM, AND THEIR USE | BOEHRINGER INGELHEIM KG (DE) | 1985-02-13 | — | — | EP | disclosed |
| EP-0073931-A1 | Anilino-1,2,3-triazole derivatives, medicaments containing them, process for preparing them, and their use | BOEHRINGER INGELHEIM KG (DE) | 1983-03-16 | — | — | EP | disclosed |