Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | STAT1 | P42224 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11040213 | 0.90 | IDO1 (0.43) | MAPTSMN1; SMN2GAATP53ALDH1A1 | |
| SCHEMBL11041382 | 0.84 | TP53 (0.49) | MAPTSMN1; SMN2GAATP53POLB | |
| SCHEMBL11044671 | 0.82 | POLB (0.49) | MAPTSMN1; SMN2GAATP53POLB | |
| SCHEMBL10981872 | 0.81 | GAA (0.66) | MAPTSMN1; SMN2GAATP53POLB | |
| SCHEMBL11038855 | 0.79 | TP53 (0.63) | SMN1; SMN2GAATP53POLBALDH1A1 | |
| SCHEMBL11039631 | 0.79 | TP53 (0.49) | MAPTSMN1; SMN2GAATP53NPC1 | |
| SCHEMBL11044738 | 0.79 | TP53 (0.49) | SMN1; SMN2GAATP53ALDH1A1TSHR | |
| SCHEMBL11096860 | 0.79 | SMN1; SMN2 (0.55) | SMN1; SMN2TP53POLBALDH1A1MAPK1 | |
| SCHEMBL11095871 | 0.78 | TP53 (0.54) | SMN1; SMN2GAATP53ALDH1A1KMT2A | |
| SCHEMBL11041232 | 0.75 | KMT2A (0.49) | MAPTSMN1; SMN2TP53ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0073931-B1 | ANILINO-1,2,3-TRIAZOLE DERIVATIVES, MEDICAMENTS CONTAINING THEM, PROCESS FOR PREPARING THEM, AND THEIR USE | BOEHRINGER INGELHEIM KG (DE) | 1985-02-13 | — | — | EP | disclosed |
| EP-0073931-A1 | Anilino-1,2,3-triazole derivatives, medicaments containing them, process for preparing them, and their use | BOEHRINGER INGELHEIM KG (DE) | 1983-03-16 | — | — | EP | disclosed |