SCHEMBL11045241

SCHEMBL11045241

C=CCc1ccc(OCC(O)CO)c(OC)c1

nearest known ligand 0.87

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.87
LMNA P02545 4/20 0.87
MEN1 O00255 4/20 0.87
KMT2A Q03164 4/20 0.87
SMN1; SMN2 Q16637 3/20 0.87
HTT P42858 2/20 0.87
MAPT P10636 2/20 0.87
KDM4E B2RXH2 1/20 0.87
GAA P10253 1/20 0.87
TSHR P16473 2/20 0.75
NPC1 O15118 2/20 0.75
RAB9A P51151 2/20 0.75
TP53 P04637 1/20 0.75
PPARA Q07869 3/20 0.63
PPARG P37231 1/20 0.63
PPARD Q03181 1/20 0.63
PKM P14618 1/20 0.59
ATM Q13315 1/20 0.59
AGTR1 P30556 1/20 0.56
CYP1A2 P05177 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17857331 0.89 ALDH1A1 (0.68) ALDH1A1LMNAMEN1KMT2ASMN1; SMN2
SCHEMBL11593471 0.88 ALDH1A1 (0.85) ALDH1A1LMNAMEN1KMT2ASMN1; SMN2
SCHEMBL11594572 0.88 ALDH1A1 (0.85) ALDH1A1LMNAMEN1KMT2ASMN1; SMN2
SCHEMBL23832195 0.87 ALDH1A1 (0.83) ALDH1A1LMNAMEN1KMT2ASMN1; SMN2
SCHEMBL25548814 0.87 ALDH1A1 (0.83) ALDH1A1LMNAMEN1KMT2ASMN1; SMN2
SCHEMBL28224427 0.86 ALDH1A1 (0.82) ALDH1A1LMNAMEN1KMT2ASMN1; SMN2
SCHEMBL21793229 0.84 ALDH1A1 (0.77) ALDH1A1LMNAMEN1KMT2ASMN1; SMN2
SCHEMBL30001190 0.84 ALDH1A1 (0.77) ALDH1A1LMNAMEN1KMT2ASMN1; SMN2
SCHEMBL28069114 0.83 ALDH1A1 (0.76) ALDH1A1LMNAMEN1KMT2ASMN1; SMN2
SCHEMBL22435156 0.83 ALDH1A1 (0.75) ALDH1A1LMNAMEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117986582-A Bio-based high-toughness self-repairing flexible resin and preparation method thereof 江南大学 2024-05-07 CN claimed
CN-116096787-B Co-modified organopolysiloxane and use thereof 陶氏东丽株式会社 2024-10-18 CN disclosed
CN-117986582-A Bio-based high-toughness self-repairing flexible resin and preparation method thereof 江南大学 2024-05-07 CN disclosed
US-20230331924-A1 CO-MODIFIED ORGANOPOLYSILOXANE AND USE THEREOF DOW TORAY CO., LTD. (JP) 2023-10-19 US disclosed
EP-4219596-A1 CO-MODIFIED ORGANOPOLYSILOXANE AND USE THEREOF Dow Toray Co., Ltd. (JP) 2023-08-02 EP disclosed
CN-116096787-A Co-modified organopolysiloxane and use thereof 陶氏东丽株式会社 2023-05-09 CN disclosed
WO-2022065520-A1 CO-MODIFIED ORGANOPOLYSILOXANE AND USE THEREOF ダウ・東レ株式会社 2022-03-31 WO disclosed
CN-105189430-B High-purity glycerol derivatives containing monoene and its manufacturing method 道康宁东丽株式会社 2018-08-10 CN disclosed
CN-104136498-B Novel liquid organopolysiloxanes and use thereof 道康宁东丽株式会社 2017-06-20 CN disclosed
CN-104136499-B Novel co-modified organopolysiloxane, and treatment agent and external preparation comprising the same 道康宁东丽株式会社 2017-06-06 CN disclosed
CN-103619915-B List or the derivative modified organopolysiloxane elastomers of Glycerol dimer and utilization thereof DOW CORNING TORAY CO.,LTD. (JP) 2015-12-23 CN disclosed
CN-103619915-A Organopolysiloxane elastomer modified with mono-/diglycerin derivative, and use therefor DOW CORNING TORAY CO LTD 2014-03-05 CN disclosed
CN-103619916-A Novel organopolysiloxane elastomers and their use DOW CORNING TORAY CO LTD 2014-03-05 CN disclosed
US-4474963-A PHASE TRANSFER CATALYSTS W. R. GRACE & CO. (US) 1984-10-02 US disclosed
US-3975324-A VULCANIZABLE POLYURETHANE ELASTOMER AMERICAN CYANAMID COMPANY (US) 1976-08-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230331924-A1 CO-MODIFIED ORGANOPOLYSILOXANE AND USE THEREOF MGLL, LIPA, DAGLB ALDH1A1 2086/4885LMNA 337/4885MEN1 1339/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.