Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.77 |
| ▸ | LMNA | P02545 | 5/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.77 |
| ▸ | HTT | P42858 | 2/20 | 0.77 |
| ▸ | MEN1 | O00255 | 2/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.77 |
| ▸ | GAA | P10253 | 1/20 | 0.77 |
| ▸ | MAPT | P10636 | 1/20 | 0.77 |
| ▸ | TSHR | P16473 | 3/20 | 0.67 |
| ▸ | NPC1 | O15118 | 1/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.60 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.60 |
| ▸ | HTR1A | P08908 | 2/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30001190 | 1.00 | ALDH1A1 (0.77) | ALDH1A1LMNASMN1; SMN2KDM4EHTT | |
| SCHEMBL7318817 | 0.86 | LMNA (0.55) | ALDH1A1LMNASMN1; SMN2KDM4EHTT | |
| SCHEMBL11593468 | 0.85 | ALDH1A1 (0.69) | ALDH1A1LMNASMN1; SMN2KDM4EHTT | |
| Hydrochloric Acid SCHEMBL11590784 | 0.85 | ALDH1A1 (0.67) | ALDH1A1LMNASMN1; SMN2KDM4EHTT | |
| SCHEMBL11858698 | 0.84 | ADRB2 (0.53) | ALDH1A1LMNASMN1; SMN2KDM4EHTT | |
| SCHEMBL11045241 | 0.84 | ALDH1A1 (0.87) | ALDH1A1LMNASMN1; SMN2KDM4EHTT | |
| SCHEMBL28224427 | 0.83 | ALDH1A1 (0.82) | ALDH1A1LMNASMN1; SMN2KDM4EHTT | |
| SCHEMBL11594572 | 0.83 | ALDH1A1 (0.85) | ALDH1A1LMNASMN1; SMN2KDM4EHTT | |
| SCHEMBL11593471 | 0.83 | ALDH1A1 (0.85) | ALDH1A1LMNASMN1; SMN2KDM4EHTT | |
| SCHEMBL20552945 | 0.82 | KMT2A (0.51) | ALDH1A1LMNASMN1; SMN2KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200261442-A1 | TARGETED DRUG RESCUE WITH NOVEL COMPOSITIONS, COMBINATIONS, AND METHODS THEREOF | VEPACHEDU SREENIVASARAO (US) | 2020-08-20 | — | — | US | disclosed |
| US-20200069674-A1 | TARGETED DRUG RESCUE WITH NOVEL COMPOSITIONS, COMBINATIONS, AND METHODS THEREOF | Exciva GmbH (DE) | 2020-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200069674-A1 | TARGETED DRUG RESCUE WITH NOVEL COMPOSITIONS, COMBINATIONS, AND METHODS THEREOF | HTR2A, HTR2C, CYP3A43 | ALDH1A1 235/4885LMNA 1421/4885SMN1; SMN2 955/4885 |
| US-20200261442-A1 | TARGETED DRUG RESCUE WITH NOVEL COMPOSITIONS, COMBINATIONS, AND METHODS THEREOF | HTR2C, HTR2A, HTR3A | ALDH1A1 501/4885LMNA 2085/4885SMN1; SMN2 676/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.