Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7092135 | 0.85 | ADRA2C (0.42) | LMNAALDH1A1ADRA2CGABRA1GABRB2 | |
| SCHEMBL4059911 | 0.81 | ADRA2C (0.47) | LMNAALDH1A1ADRA2CGABRA1GABRB2 | |
| SCHEMBL30589993 | 0.81 | ADRA2C (0.47) | LMNAALDH1A1ADRA2CGABRA1GABRB2 | |
| SCHEMBL9284485 | 0.81 | ADRA2C (0.41) | LMNAALDH1A1ADRA2CGABRA1GABRB2 | |
| SCHEMBL9806298 | 0.80 | TSHR (0.50) | LMNAALDH1A1ADRA2CGABRA1GABRB2 | |
| SCHEMBL6269535 | 0.79 | GABRA1 (0.46) | LMNAALDH1A1ADRA2CGABRA1GABRB2 | |
| SCHEMBL10663159 | 0.79 | LMNA (0.47) | LMNAALDH1A1ADRB2ADRB1TSHR | |
| SCHEMBL3924209 | 0.79 | LMNA (0.50) | LMNAALDH1A1GABRA1GABRB2TSHR | |
| SCHEMBL3924212 | 0.79 | LMNA (0.50) | LMNAALDH1A1GABRA1GABRB2TSHR | |
| SCHEMBL9666849 | 0.78 | ALDH1A1 (0.40) | LMNAALDH1A1ADRA2CGABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0045571-B1 | PROCESS FOR THE PRODUCTION OF PHENYL SUBSTITUTED ALDEHYDES AND OF PHENYL SUBSTITUTED ALCOHOLS | BUSH BOAKE ALLEN Limited (GB) | 1985-06-26 | — | — | EP | claimed |
| EP-0045571-A1 | Process for the production of phenyl substituted aldehydes and of phenyl substituted alcohols | BUSH BOAKE ALLEN Limited (GB) | 1982-02-10 | — | — | EP | claimed |