SCHEMBL11045262

SCHEMBL11045262

CN(NC(=O)O)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 3/20 0.56
ALDH1A1 P00352 3/20 0.49
RAB9A P51151 4/20 0.45
NPC1 O15118 3/20 0.45
HPGD P15428 1/20 0.45
NPSR1 Q6W5P4 2/20 0.44
KMT2A Q03164 3/20 0.43
MEN1 O00255 2/20 0.43
GLA P06280 1/20 0.42
TSHR P16473 1/20 0.42
TACR3 P29371 1/20 0.41
L3MBTL1 Q9Y468 3/20 0.41
TDP1 Q9NUW8 2/20 0.41
MAPT P10636 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
KDM4E B2RXH2 1/20 0.41
TP53 P04637 1/20 0.41
GAA P10253 1/20 0.41
THRB P10828 1/20 0.41
PKM P14618 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5144331 0.98 HTT (0.54) HTTALDH1A1RAB9ANPC1HPGD
SCHEMBL8505339 0.84 HTT (0.54) HTTALDH1A1RAB9ANPC1HPGD
SCHEMBL9333402 0.83 HTT (0.53) HTTALDH1A1RAB9ANPC1HPGD
SCHEMBL1520692 0.83 HTT (0.53) HTTALDH1A1RAB9ANPC1HPGD
SCHEMBL11369151 0.81 TDP1 (0.59) HTTALDH1A1RAB9ANPC1HPGD
SCHEMBL17494839 0.79 ALDH1A1 (0.42) HTTALDH1A1NPC1NPSR1MAPT
SCHEMBL11651548 0.78 HTT (0.47) HTTALDH1A1RAB9ANPC1HPGD
SCHEMBL18305859 0.76 KMT2A (0.52) HTTALDH1A1RAB9ANPC1NPSR1
Bicarbonate SCHEMBL7649134 0.75 HPGD (0.64) HTTALDH1A1RAB9ANPC1HPGD
SCHEMBL28705821 0.75 AKT1 (0.55) HTTALDH1A1RAB9ANPC1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9527744-B2 Method for manufacturing reduced graphene oxide using solid hydrazine derivative Sogang University Research Foundation (KR) 2016-12-27 US disclosed
US-9469603-B2 Reaction product of hydrazine derivatives and carbon dioxide Sogang University Research Foundation (KR) 2016-10-18 US disclosed
US-9469603-B2 Reaction product of hydrazine derivatives and carbon dioxide Sogang University Research Foundation (KR) 2016-10-18 US disclosed
US-20150344311-A1 METHOD FOR MANUFACTURING REDUCED GRAPHENE OXIDE USING SOLID HYDRAZINE DERIVATIVE Sogang University Research Foundation (KR) 2015-12-03 US disclosed
US-20150094490-A1 REACTION PRODUCT OF HYDRAZINE DERIVATIVES AND CARBON DIOXIDE Sogang University Research Foundation (KR) 2015-04-02 US disclosed
US-20150094490-A1 REACTION PRODUCT OF HYDRAZINE DERIVATIVES AND CARBON DIOXIDE Sogang University Research Foundation (KR) 2015-04-02 US disclosed
WO-2014077602-A1 METHOD FOR MANUFACTURING REDUCED GRAPHENE OXIDE USING SOLID HYDRAZINE DERIVATIVE 서강대학교산학협력단 (KR) 2014-05-22 WO disclosed
WO-2013137494-A1 REACTION PRODUCT OF HYDRAZINE DERIVATIVES AND CARBON DIOXIDE 서강대학교 산학협력단 (KR) 2013-09-19 WO disclosed
CN-1169986-A 2.9-diamino-and 2-amino-8-carbamoyl-4-hydroxy-aldanoic acid amide derivatives CIBA GEIGY AG (CH) 1998-01-14 CN disclosed
US-4459227-A Para-hydroxyphenylhydrazines as in situ precursors of iminoquinones and quinones DUKE UNIVERSITY (US) 1984-07-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150094490-A1 REACTION PRODUCT OF HYDRAZINE DERIVATIVES AND CARBON DIOXIDE NOX5, HAO2, CA5A HTT 672/4885ALDH1A1 878/4885RAB9A 2008/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.