Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | TACR3 | P29371 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11045262 | 0.84 | HTT (0.56) | HTTALDH1A1RAB9ANPC1HPGD | |
| Hydrochloric Acid SCHEMBL5144331 | 0.83 | HTT (0.54) | HTTALDH1A1RAB9ANPC1HPGD | |
| SCHEMBL9333402 | 0.81 | HTT (0.53) | HTTALDH1A1RAB9ANPC1HPGD | |
| SCHEMBL1520692 | 0.81 | HTT (0.53) | HTTALDH1A1RAB9ANPC1HPGD | |
| SCHEMBL12305493 | 0.80 | KMT2A (0.53) | HTTALDH1A1MTNR1AMTNR1BNAPRT | |
| SCHEMBL11369151 | 0.79 | TDP1 (0.59) | HTTALDH1A1HSD17B10RAB9ANPC1 | |
| SCHEMBL9130749 | 0.78 | MTNR1A (0.47) | HTTALDH1A1MTNR1AMTNR1BNAPRT | |
| SCHEMBL20893396 | 0.77 | MTNR1A (0.46) | HTTALDH1A1MTNR1AMTNR1BNAPRT | |
| SCHEMBL14989351 | 0.77 | KMT2A (0.51) | HTTALDH1A1MTNR1AMTNR1BNAPRT | |
| SCHEMBL10416068 | 0.77 | MTNR1A (0.46) | HTTALDH1A1MTNR1AMTNR1BNAPRT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100234363-A1 | HETEROCYCLIC DERIVATIVE HAVING INHIBITORY ACTIVITY ON TYPE-I 11 DATA-HYDROXYSTEROID DEHYDROGENASE | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2010-09-16 | — | — | US | disclosed |
| US-20100234363-A1 | HETEROCYCLIC DERIVATIVE HAVING INHIBITORY ACTIVITY ON TYPE-I 11 DATA-HYDROXYSTEROID DEHYDROGENASE | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2010-09-16 | — | — | US | disclosed |
| EP-2208728-A1 | HETEROCYCLIC DERIVATIVE HAVING INHIBITORY ACTIVITY ON TYPE-I 11 -HYDROXYSTEROID DEHYDROGENASE | Institute Of Medicinal Molecular Design, Inc. (JP) | 2010-07-21 | — | — | EP | disclosed |
| CN-1152866-C | Benzimidazoles, production thereof and use thereof medicaments | ���ָ��Ӣ��ķ�������Ϲ�˾ | 2004-06-09 | — | — | CN | disclosed |
| CN-1308614-A | Benzimidazoles, production thereof and use thereof medicaments | BOEHRINGER INGELHEIM PHAMA KG (DE) | 2001-08-15 | — | — | CN | disclosed |
| US-5932592-A | ETHYL 4-(3,4-DIMETHOXYPHENYL)-6,7-DIMETHOXY-2-(1,2,4-TRIAZOLE-1-YLME THYL)QUINOLINE-3-CARBOXYLATE; ANTIINFLAMMATORY AND ANTIARTHRITIC AGENT | TAKEDA CHEMICAL IND., LTD. (JP) | 1999-08-03 | — | — | US | disclosed |
| US-4676803-A | Reactive azo dyestuffs, free from anionic groups and containing a basic group and halogenotriazinyl radical and useful for dyeing cellulose/polyester | BAYER AKTIENGESELLSCHAFT (DE) | 1987-06-30 | — | — | US | disclosed |
| US-4503224-A | FIBER-REACTIVE, COTTON-POLYESTER BLENDS | BAYER AKTIENGESELLSCHAFT (DE) | 1985-03-05 | — | — | US | disclosed |
| EP-0022209-A2 | Fluor-triazine dyestuffs and their use in dyeing cellulosic fibrous materials | BAYER AG (DE) | 1981-01-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234363-A1 | HETEROCYCLIC DERIVATIVE HAVING INHIBITORY ACTIVITY ON TYPE-I 11 DATA-HYDROXYSTEROID DEHYDROGENASE | HSD11B1, HSD11B2, HSD3B1 | HTT 4484/4885ALDH1A1 165/4885MTNR1A 3539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.