Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NOS1 | P29475 | 3/20 | 0.46 |
| ▸ | NOS3 | P29474 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.43 |
| ▸ | HTR3B | O95264 | 2/20 | 0.43 |
| ▸ | HTR3A | P46098 | 2/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.43 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.43 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.43 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.43 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8773393 | 1.00 | KMT2A (0.48) | KMT2AMEN1NOS1NOS3MAPT | |
| SCHEMBL673513 | 0.83 | ALDH1A1 (0.45) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL11796725 | 0.82 | NOS3 (0.50) | KMT2AMEN1NOS1NOS3MAPT | |
| SCHEMBL11882734 | 0.79 | KMT2A (0.41) | KMT2AMEN1NOS1NOS3MAPT | |
| SCHEMBL11882741 | 0.79 | KMT2A (0.41) | KMT2AMEN1NOS1NOS3MAPT | |
| SCHEMBL14975956 | 0.78 | KMT2A (0.49) | KMT2AMEN1NOS1NOS3MAPT | |
| SCHEMBL14975958 | 0.78 | KMT2A (0.49) | KMT2AMEN1NOS1NOS3MAPT | |
| SCHEMBL15516659 | 0.77 | ALDH1A1 (0.48) | KMT2AMEN1MAPTALDH1A1HSP90AA1 | |
| SCHEMBL8638472 | 0.77 | ALDH1A1 (0.48) | KMT2AMEN1MAPTALDH1A1HIF1A | |
| SCHEMBL20419616 | 0.77 | ALDH1A1 (0.48) | KMT2AMEN1MAPTALDH1A1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013077654-A1 | IRIDIUM (III) COMPLEX AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME | 주식회사 두산 (KR) | 2013-05-30 | — | — | WO | disclosed |
| WO-2013077654-A1 | IRIDIUM (III) COMPLEX AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME | 주식회사 두산 (KR) | 2013-05-30 | — | — | WO | disclosed |
| US-4448975-A | Process for the preparation of substituted amidines | GENERAL ELECTRIC COMPANY (US) | 1984-05-15 | — | — | US | disclosed |
| US-4321202-A | 1-Methyl-2(alkylimino)pyrrolidines and 1-methyl 2(cycloalkylimino) pyrrolidines | GENERAL ELECTRIC COMPANY (US) | 1982-03-23 | — | — | US | disclosed |