SCHEMBL673513

SCHEMBL673513

CN(C)C(=Nc1ccccc1N=C(c1ccccc1)N(C)C)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.45
MAPT P10636 1/20 0.45
KMT2A Q03164 3/20 0.45
HSP90AA1 P07900 1/20 0.39
HPGD P15428 3/20 0.37
GFER P55789 1/20 0.37
LMNA P02545 1/20 0.36
KDM4E B2RXH2 2/20 0.36
HSD17B10 Q99714 1/20 0.36
RAB9A P51151 2/20 0.35
NPC1 O15118 1/20 0.35
MEN1 O00255 1/20 0.35
GAA P10253 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8773393 0.83 KMT2A (0.48) ALDH1A1MAPTKMT2AHSP90AA1LMNA
SCHEMBL11045409 0.83 KMT2A (0.48) ALDH1A1MAPTKMT2AHSP90AA1LMNA
SCHEMBL8638472 0.77 ALDH1A1 (0.48) ALDH1A1MAPTKMT2AHSP90AA1HPGD
SCHEMBL20419616 0.77 ALDH1A1 (0.48) ALDH1A1MAPTKMT2AHSP90AA1HPGD
SCHEMBL15516659 0.77 ALDH1A1 (0.48) ALDH1A1MAPTKMT2AHSP90AA1HPGD
SCHEMBL14999390 0.77 ALDH1A1 (0.48) ALDH1A1MAPTKMT2AHSP90AA1HPGD
SCHEMBL673966 0.72 KMT2A (0.44) ALDH1A1MAPTKMT2AHSP90AA1HPGD
SCHEMBL12562448 0.72 KMT2A (0.44) ALDH1A1MAPTKMT2AHSP90AA1HPGD
SCHEMBL11918907 0.72 KMT2A (0.44) ALDH1A1MAPTKMT2AHSP90AA1HPGD
SCHEMBL18661813 0.72 KMT2A (0.44) ALDH1A1MAPTKMT2AHSP90AA1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7968652-B2 Modified conjugated diene copolymer, rubber compositions and tires BRIDGESTONE CORPORATION (JP) 2011-06-28 US claimed
US-7671136-B2 Modified polymers prepared with lanthanide-based catalysts BRIDGESTONE CORPORATION (JP) 2010-03-02 US claimed
US-20090292043-A1 MODIFIED CONJUGATED DIENE COPOLYMER, RUBBER COMPOSITIONS AND TIRES BRIDGESTONE CORPORATION (JP) 2009-11-26 US claimed
US-20060025539-A1 Modified polymers prepared with lanthanide-based catalysts OZAWA YOICHI 2006-02-02 US claimed
US-6977281-B1 Modified polymers prepared with lanthanide-based catalysts BRIDGESTONE CORPORATION (JP) 2005-12-20 US claimed
CN-111344314-B Modified conjugated diene polymer and preparation method thereof 株式会社LG化学 2023-01-03 CN disclosed
EP-1873168-B1 MODIFIED CONJUGATED DIENE COPOLYMER, RUBBER COMPOSITIONS AND TIRES BRIDGESTONE CORP (JP) 2012-12-12 EP disclosed
US-7968652-B2 Modified conjugated diene copolymer, rubber compositions and tires BRIDGESTONE CORPORATION (JP) 2011-06-28 US disclosed
US-7671136-B2 Modified polymers prepared with lanthanide-based catalysts BRIDGESTONE CORPORATION (JP) 2010-03-02 US disclosed
US-20090292043-A1 MODIFIED CONJUGATED DIENE COPOLYMER, RUBBER COMPOSITIONS AND TIRES BRIDGESTONE CORPORATION (JP) 2009-11-26 US disclosed
EP-1873168-A1 MODIFIED CONJUGATED DIENE COPOLYMER, RUBBER COMPOSITIONS AND TIRES Bridgestone Corporation (JP) 2008-01-02 EP disclosed
EP-1237935-B1 MODIFIED POLYMERS PREPARED WITH LANTHANIDE-BASED CATALYSTS BRIDGESTONE CORP (JP) 2007-01-24 EP disclosed
US-20060025539-A1 Modified polymers prepared with lanthanide-based catalysts OZAWA YOICHI 2006-02-02 US disclosed
US-6977281-B1 Modified polymers prepared with lanthanide-based catalysts BRIDGESTONE CORPORATION (JP) 2005-12-20 US disclosed