Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | EDNRB | P24530 | 2/20 | 0.33 |
| ▸ | EDNRA | P25101 | 2/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CDK7 | P50613 | 1/20 | 0.33 |
| ▸ | CCNH | P51946 | 1/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 3/20 | 0.32 |
| ▸ | F2 | P00734 | 2/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11052920 | 0.89 | CA1 (0.42) | TRPV4CA1CA2ALDH1A1TSHR | |
| SCHEMBL7129180 | 0.82 | KDM4E (0.44) | TRPV4CA1CA2ALDH1A1KDM4E | |
| SCHEMBL197705 | 0.81 | TRPV4 (0.41) | TRPV4CA1CA2ALDH1A1CDK1 | |
| SCHEMBL2734563 | 0.80 | AKR1C4 (0.43) | CA1CA2ALDH1A1TP53ACLY | |
| SCHEMBL11690992 | 0.79 | KIF18A (0.42) | ALDH1A1TSHR | |
| SCHEMBL3932613 | 0.75 | TRPV4 (0.53) | TRPV4ALDH1A1CDK1CCNB1CCNA2 | |
| SCHEMBL1037698 | 0.75 | ALDH1A1 (0.39) | TRPV4ALDH1A1TSHRACLYKDM4E | |
| SCHEMBL29683254 | 0.73 | ALDH1A1 (0.50) | TRPV4CA1CA2ALDH1A1TSHR | |
| SCHEMBL7526380 | 0.73 | TRPV4 (0.34) | TRPV4ALDH1A1TSHR | |
| SCHEMBL5704866 | 0.73 | ALDH1A1 (0.50) | TRPV4CA1CA2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4438245-A | FOR LIGHT SENSITIVE ELEMENTS | FUJI PHOTO FILM CO., LTD. (JP) | 1984-03-20 | — | — | US | disclosed |