Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | VCAM1 | P19320 | 5/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | CCR6 | P51684 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7374445 | 0.82 | KIF18A (0.44) | KIF18AVCAM1TSHRMAPK1ALDH1A1 | |
| SCHEMBL3612247 | 0.81 | TDP1 (0.54) | CYP1A2VCAM1TSHRMAPK1ALDH1A1 | |
| SCHEMBL11045768 | 0.79 | TRPV4 (0.44) | TSHRALDH1A1 | |
| SCHEMBL12263626 | 0.79 | TRPV4 (0.41) | KIF18AVCAM1TSHRMAPK1ALDH1A1 | |
| SCHEMBL11333391 | 0.77 | TSHR (0.39) | CYP1A2VCAM1TSHRALDH1A1CRHBP | |
| SCHEMBL3814710 | 0.76 | KIF18A (0.39) | KIF18ACYP1A2VCAM1TSHRMAPK1 | |
| SCHEMBL3864393 | 0.76 | TSHR (0.54) | CYP1A2VCAM1TSHRMAPK1ALDH1A1 | |
| SCHEMBL18829958 | 0.76 | CYP1A2 (0.55) | CYP1A2VCAM1TSHRMAPK1ALDH1A1 | |
| SCHEMBL2062571 | 0.75 | MAPK1 (0.58) | KIF18AVCAM1TSHRMAPK1ALDH1A1 | |
| SCHEMBL1052777 | 0.75 | KIF18A (0.64) | KIF18AVCAM1TSHRMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4008208-A | Compositions having inhibited ability to promote platelet aggregation or fibrin clot formation | THE UPJOHN COMPANY (US) | 1977-02-15 | — | — | US | disclosed |
| US-3975371-A | Aromatic azo sulfonylnitrene compounds | THE UPJOHN COMPANY (US) | 1976-08-17 | — | — | US | disclosed |
| US-3954583-A | Photochemical process | THE UPJOHN COMPANY (US) | 1976-05-04 | — | — | US | disclosed |