Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.42 |
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 12/20 | 0.41 |
| ▸ | MEN1 | O00255 | 12/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 12/20 | 0.41 |
| ▸ | LMNA | P02545 | 6/20 | 0.41 |
| ▸ | HTT | P42858 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | CCR6 | P51684 | 1/20 | 0.40 |
| ▸ | HTR1E | P28566 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11564649 | 0.88 | RORC (0.46) | SMN1; SMN2RAB9ANPC1MAPK1TP53 | |
| SCHEMBL11045834 | 0.86 | KMT2A (0.46) | SMN1; SMN2RAB9ANPC1MAPK1TP53 | |
| SCHEMBL11049200 | 0.86 | MEN1 (0.44) | SMN1; SMN2RAB9ANPC1MAPK1TP53 | |
| SCHEMBL11054922 | 0.85 | MAPT (0.57) | SMN1; SMN2RAB9ANPC1TP53MAPT | |
| SCHEMBL11050028 | 0.82 | BRAF (0.46) | SMN1; SMN2RAB9ANPC1MAPK1TP53 | |
| SCHEMBL11565436 | 0.81 | HDAC1 (0.39) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL11566980 | 0.80 | SMN1; SMN2 (0.41) | SMN1; SMN2RAB9ANPC1TP53MAPT | |
| SCHEMBL8161671 | 0.76 | CYP1A2 (0.55) | SMN1; SMN2RAB9ANPC1MAPK1TP53 | |
| SCHEMBL11565621 | 0.75 | KCNQ3 (0.47) | SMN1; SMN2RAB9ANPC1TP53ALDH1A1 | |
| SCHEMBL11558200 | 0.74 | CETP (0.41) | SMN1; SMN2RAB9ANPC1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0052473-B1 | N-SUBSTITUTED PHENYL-1-METHYLCYCLOPROPANECARBOXAMIDES, THEIR PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-08-22 | — | — | EP | disclosed |
| US-4447260-A | N-Substituted phenyl-1-methylcyclopropanecarboxamides, and their herbicidal use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-05-08 | — | — | US | disclosed |
| EP-0052473-A2 | N-Substituted phenyl-1-methylcyclopropanecarboxamides, their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-05-26 | — | — | EP | disclosed |