Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 5/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | TSHR | P16473 | 3/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | GALR3 | O60755 | 1/20 | 0.31 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11025913 | 0.87 | SLC29A1 (0.33) | KMT2ALMNATSHRHSD17B10MAPT | |
| SCHEMBL11029550 | 0.86 | PDGFRB (0.34) | KITTSHRHSD17B10ALDH1A1KDM4E | |
| SCHEMBL11023760 | 0.84 | KIT (0.34) | KITLMNATSHRALDH1A1HPGD | |
| SCHEMBL11046910 | 0.82 | HRH4 (0.38) | LMNATSHRALDH1A1HPGDHTT | |
| SCHEMBL11028075 | 0.82 | HRH4 (0.39) | LMNATSHRALDH1A1HPGDHTT | |
| SCHEMBL11052623 | 0.82 | HRH4 (0.41) | LMNATSHRALDH1A1HPGDHTT | |
| SCHEMBL11021987 | 0.82 | SLC29A1 (0.33) | MAPTSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL11312367 | 0.81 | ACACB (0.35) | KITLMNATSHRALDH1A1HPGD | |
| SCHEMBL11030154 | 0.80 | SLC29A1 (0.32) | — | |
| SCHEMBL11026067 | 0.80 | NPC1 (0.31) | CDK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4478833-A | ANTICOAGULANTS | DR. KARL THOMAE GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1984-10-23 | — | — | US | disclosed |
| EP-0055444-A2 | Trisubstituted pyrimido(5,4-d)pyrimidines, their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1982-07-07 | — | — | EP | disclosed |