Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LSS | P48449 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.39 |
| ▸ | SLC9A3 | P48764 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | FPR2 | P25090 | 3/20 | 0.36 |
| ▸ | PROKR1 | Q8TCW9 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | LIPE | Q05469 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11050109 | 0.88 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1SLC6A4SLC6A2SLC6A3 | |
| Fumaric Acid SCHEMBL11051336 | 0.87 | HRH2 (0.44) | ALDH1A1L3MBTL1LSSLIPE | |
| SCHEMBL11048663 | 0.81 | HRH3 (0.45) | SLC6A2SLC6A3KCNH2 | |
| SCHEMBL10261843 | 0.73 | HTR2C (0.58) | L3MBTL1SLC6A4SLC6A2SLC6A3HTR2C | |
| SCHEMBL17848470 | 0.73 | HTR2C (0.58) | L3MBTL1SLC6A4SLC6A2SLC6A3HTR2C | |
| SCHEMBL20788247 | 0.73 | HTR2C (0.58) | L3MBTL1SLC6A4SLC6A2SLC6A3HTR2C | |
| SCHEMBL11053024 | 0.71 | L3MBTL1 (0.57) | ALDH1A1L3MBTL1 | |
| SCHEMBL11048973 | 0.71 | HRH3 (0.39) | ALDH1A1SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL11049174 | 0.71 | RAB9A (0.47) | KCNH2 | |
| SCHEMBL8302495 | 0.70 | HRH3 (0.63) | SLC6A4SLC6A2SLC6A3HTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4451473-A | 3,7-Diazabicyclo [3.3.1] nonanes having anti-arrhythmic activity | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1984-05-29 | — | — | US | claimed |