Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11049174 | 0.91 | RAB9A (0.47) | HRH3MAPK1RAB9ACHRNA7 | |
| SCHEMBL11048663 | 0.88 | HRH3 (0.45) | HRH3CARM1PRMT6SLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL11050109 | 0.84 | ALDH1A1 (0.39) | HRH3SLC6A2SLC6A3ALDH1A1SLC6A4 | |
| Hydrochloric Acid SCHEMBL11050146 | 0.82 | KMT2A (0.46) | HRH3SLC6A2SLC6A3MAPK1SLC6A4 | |
| Hydrochloric Acid SCHEMBL11045710 | 0.79 | SLC6A4 (0.38) | SLC6A2SLC6A3GRIN1GRIN2BALDH1A1 | |
| SCHEMBL20090859 | 0.78 | GRIN1 (0.56) | CARM1PRMT6SLC6A2SLC6A3GRIN1 | |
| Fumaric Acid SCHEMBL11048023 | 0.77 | HRH1 (0.41) | HRH3KDM4EALDH1A1MAPK1CHRM4 | |
| Fumaric Acid SCHEMBL11048014 | 0.77 | HRH1 (0.41) | HRH3KDM4EALDH1A1MAPK1CHRM4 | |
| SCHEMBL20012540 | 0.76 | CARM1 (0.47) | HRH3CARM1PRMT6SLC6A2SLC6A3 | |
| SCHEMBL11046189 | 0.76 | OPRM1 (0.48) | CARM1PRMT6CHRM2CHRM4CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4451473-A | 3,7-Diazabicyclo [3.3.1] nonanes having anti-arrhythmic activity | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1984-05-29 | — | — | US | disclosed |