Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27082399 | 0.78 | CRBN (0.41) | MAP3K14CRBNDDB1CYP19A1GAA | |
| SCHEMBL25905416 | 0.78 | CRBN (0.51) | CRBNDDB1 | |
| SCHEMBL11835120 | 0.77 | MAP3K14 (0.43) | MAP3K14CRBNDDB1CYP19A1IDO1 | |
| SCHEMBL36369 | 0.77 | MAP3K14 (0.43) | MAP3K14CRBNDDB1CYP19A1IDO1 | |
| SCHEMBL4226226 | 0.76 | MAP3K14 (0.41) | MAP3K14CRBNDDB1CYP19A1 | |
| Water SCHEMBL27852712 | 0.76 | MAP3K14 (0.41) | MAP3K14CRBNDDB1CYP19A1 | |
| SCHEMBL5086277 | 0.76 | MAP3K14 (0.41) | MAP3K14CRBNDDB1CYP19A1 | |
| SCHEMBL4226223 | 0.76 | MAP3K14 (0.41) | MAP3K14CRBNDDB1CYP19A1 | |
| SCHEMBL18065790 | 0.74 | MAP3K14 (0.40) | MAP3K14CRBNDDB1CYP19A1GAA | |
| SCHEMBL625564 | 0.74 | MAP3K14 (0.40) | MAP3K14CRBNDDB1CYP19A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506765-B1 | Cosmetic composition containing stabilized metallic particles, optionally coated | OREAL (FR) | 2007-07-25 | — | — | EP | disclosed |
| US-4444674-A | Granular bleach activator compositions and detergent compositions containing them | THE PROCTER & GAMBLE COMPANY (US) | 1984-04-24 | — | — | US | disclosed |