SCHEMBL625564

SCHEMBL625564

O=C1CC(S(=O)(=O)OO)C(=O)N1

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAP3K14 Q99558 1/20 0.40
CRBN Q96SW2 2/20 0.33
IDO1 P14902 1/20 0.32
CYP19A1 P11511 1/20 0.32
DDB1 Q16531 1/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
PKM P14618 1/20 0.31
MEN1 O00255 1/20 0.31
APEX1 P27695 1/20 0.31
KMT2A Q03164 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
GAA P10253 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18065790 0.79 MAP3K14 (0.40) MAP3K14CRBNCYP19A1DDB1LMNA
SCHEMBL36369 0.78 MAP3K14 (0.43) MAP3K14CRBNIDO1CYP19A1DDB1
SCHEMBL5086277 0.77 MAP3K14 (0.41) MAP3K14CRBNCYP19A1DDB1MEN1
Water SCHEMBL27852712 0.77 MAP3K14 (0.41) MAP3K14CRBNCYP19A1DDB1MEN1
SCHEMBL30158537 0.77 MAP3K14 (0.41) MAP3K14CRBNCYP19A1DDB1MEN1
SCHEMBL4226226 0.77 MAP3K14 (0.41) MAP3K14CRBNCYP19A1DDB1MEN1
SCHEMBL11835120 0.74 MAP3K14 (0.43) MAP3K14CRBNIDO1CYP19A1DDB1
SCHEMBL11047080 0.74 MAP3K14 (0.43) MAP3K14CRBNIDO1CYP19A1DDB1
Bicarbonate SCHEMBL28576915 0.73 MAP3K14 (0.39) MAP3K14CRBNCYP19A1DDB1MEN1
SCHEMBL4226223 0.72 MAP3K14 (0.41) MAP3K14CRBNCYP19A1DDB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4380962-A1 PROCESS FOR THE PREPARATION OF SEMAGLUTIDE MSN Laboratories Private Limited, R&D Center (IN) 2024-06-12 EP claimed
WO-2023012829-A1 PROCESS FOR THE PREPARATION OF SEMAGLUTIDE MSN LABORATORIES PRIVATE LIMITED, R&D CENTER (IN) 2023-02-09 WO claimed
EP-2585818-A2 METHOD AND APPARATUS FOR DETECTING AND REGULATING VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) BY FORMING A HOMEOSTATIC LOOP EMPLOYING A HALF-ANTIBODY BIOSENSOR Shachar, Yehoshua (US) 2013-05-01 EP disclosed
US-8415472-B2 Water soluble photochromic compounds for labeling of biomolecules and method for detecting biomolecules using the same KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) 2013-04-09 US disclosed
WO-2011163320-A9 METHOD AND APPARATUS FOR DETECTING AND REGULATING VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) BY FORMING A HOMEOSTATIC LOOP EMPLOYING A HALF-ANTIBODY BIOSENSOR PHARMACO-KINESIS CORPORATION (US) 2012-02-16 WO disclosed
WO-2011163320-A2 METHOD AND APPARATUS FOR DETECTING AND REGULATING VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) BY FORMING A HOMEOSTATIC LOOP EMPLOYING A HALF-ANTIBODY BIOSENSOR PHARMACO-KINESIS CORPORATION (US) 2011-12-29 WO disclosed
US-20100256397-A1 WATER SOLUBLE PHOTOCHROMIC COMPOUNDS FOR LABELING OF BIOMOLECULES AND METHOD FOR DETECTING BIOMOLECULES USING THE SAME KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) 2010-10-07 US disclosed
WO-2009054608-A1 WATER SOLUBLE PHOTOCHROMIC COMPOUNDS FOR LABELING OF BIOMOLECULES AND METHOD FOR DETECTING BIOMOLECULES USING THE SAME KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) 2009-04-30 WO disclosed
WO-2006091233-A2 CELLULAR DELIVERY OF REAGENTS THAT INHIBIT GENE EXPRESSION UTILIZING THE ANTHRAX TOXIN PROTECTIVE ANTIGEN (PA) BOSTON MEDICAL CENTER CORPORATION (US) 2006-08-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100256397-A1 WATER SOLUBLE PHOTOCHROMIC COMPOUNDS FOR LABELING OF BIOMOLECULES AND METHOD FOR DETECTING BIOMOLECULES USING THE SAME MB, RBP1, TTR MAP3K14 3184/4885CRBN 1796/4885IDO1 3256/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.