SCHEMBL11047272

SCHEMBL11047272

c1ccc(C2c3ccccc3Nc3ccccc32)cc1

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HTR5A P47898 4/20 0.41
LMNA P02545 3/20 0.40
MAPT P10636 3/20 0.40
IDO1 P14902 2/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
ALDH1A1 P00352 1/20 0.39
TP53 P04637 2/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
MAPK1 P28482 1/20 0.38
HTR2B P41595 1/20 0.38
GAA P10253 2/20 0.38
EGFR P00533 1/20 0.38
HPGD P15428 1/20 0.38
ALOX12 P18054 1/20 0.38
TDO2 P48775 1/20 0.38
NOS2 P35228 1/20 0.37
TSHR P16473 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2828597 0.83 IDO1 (0.51) LMNAMAPTIDO1ALDH1A1TP53
SCHEMBL12165459 0.83 HTR5A (0.37) HTR5ALMNAMAPTIDO1MEN1
SCHEMBL31728057 0.83 IDO1 (0.51) LMNAMAPTIDO1ALDH1A1TP53
SCHEMBL23044014 0.80 MAPT (0.44) LMNAMAPTIDO1MEN1KMT2A
SCHEMBL7918631 0.79 CYP1A2 (0.48) LMNAMAPTMEN1KMT2AALDH1A1
SCHEMBL3907143 0.77 CHEK1 (0.50) LMNAMAPTMEN1KMT2AALDH1A1
SCHEMBL8539518 0.76 ALDH1A1 (0.47) IDO1ALDH1A1EGFRTSHR
SCHEMBL4430050 0.74 IDO1 (0.51) LMNAMAPTIDO1MEN1KMT2A
SCHEMBL5507339 0.74 GAA (0.49) HTR5ALMNAMAPTMEN1KMT2A
SCHEMBL15913307 0.74 CHRNA7 (0.43) HTR5ALMNAMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240215439-A1 ORGANIC MOLECULES FOR OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2024-06-27 US disclosed
US-20170263871-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND ORGANIC OPTOELECTRONIC DEVICE TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2017-09-14 US disclosed
US-20170263871-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND ORGANIC OPTOELECTRONIC DEVICE TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2017-09-14 US disclosed
US-20150236272-A1 NOVEL COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THESAME DOOSAN CORPORATION (KR) 2015-08-20 US disclosed
US-20120289884-A1 Fused Ring Diarylamino Photosensitizers for Phototherapy MALLINCKRODT LLC (US) 2012-11-15 US disclosed
US-20120289884-A1 Fused Ring Diarylamino Photosensitizers for Phototherapy MALLINCKRODT LLC (US) 2012-11-15 US disclosed
US-20120289884-A1 Fused Ring Diarylamino Photosensitizers for Phototherapy MALLINCKRODT LLC (US) 2012-11-15 US disclosed
US-4466080-A Three-dimensional patterned media FORMIGRAPHIC ENGINE CORPORATION (US) 1984-08-14 US disclosed
US-4333165-A Three-dimensional pattern making methods FORMIGRAPHIC ENGINE CORPORATION (US) 1982-06-01 US disclosed
US-4288861-A Three-dimensional systems FORMIGRAPHIC ENGINE CORPORATION (US) 1981-09-08 US disclosed
US-4078229-A Three dimensional systems SWANSON WYN K 1978-03-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240215439-A1 ORGANIC MOLECULES FOR OPTOELECTRONIC DEVICES OCIAD2, OR10J3, EPCAM HTR5A 4651/4885LMNA 1482/4885MAPT 2995/4885
US-20170263871-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND ORGANIC OPTOELECTRONIC DEVICE OR10J3, RPS10, OR51E2 HTR5A 3507/4885LMNA 1723/4885MAPT 3830/4885
US-20150236272-A1 NOVEL COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THESAME INMT, IDO1, IDO2 HTR5A 78/4885LMNA 2754/4885MAPT 673/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.