Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 3/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | FER | P16591 | 1/20 | 0.38 |
| ▸ | LTK | P29376 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31728057 | 0.81 | IDO1 (0.51) | MAPTLMNATP53CYP1A2CYP3A4 | |
| SCHEMBL2828597 | 0.81 | IDO1 (0.51) | MAPTLMNATP53CYP1A2CYP3A4 | |
| SCHEMBL11047272 | 0.80 | HTR5A (0.41) | MAPTLMNATP53CYP1A2CYP3A4 | |
| SCHEMBL8539518 | 0.74 | ALDH1A1 (0.47) | IDO1ALDH1A1EGFRGSK3B | |
| SCHEMBL12165459 | 0.73 | HTR5A (0.37) | MAPTLMNATP53CYP1A2CYP3A4 | |
| SCHEMBL17074980 | 0.69 | GSK3B (0.58) | MAPTIDO1TDO2GSK3BKDM4E | |
| SCHEMBL7012598 | 0.68 | GPR174 (0.59) | MAPTMAPK1ALDH1A1KDM4EMEN1 | |
| SCHEMBL6307527 | 0.68 | JAK2 (0.47) | MAPTLMNATP53CYP1A2CYP3A4 | |
| SCHEMBL18025754 | 0.68 | PDE4A (0.49) | MAPTIDO1TNKS2ALDH1A1TDO2 | |
| SCHEMBL3078111 | 0.68 | JAK2 (0.53) | MAPTIDO1ALDH1A1TDO2GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021042001-A1 | COMPOSITIONS AND METHODS RELATED TO DISSOLVED OXIDES | Natural Extraction Systems, LLC (US) | 2021-03-04 | — | — | WO | claimed |
| WO-2021042001-A1 | COMPOSITIONS AND METHODS RELATED TO DISSOLVED OXIDES | Natural Extraction Systems, LLC (US) | 2021-03-04 | — | — | WO | disclosed |