⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10707140 | 0.92 | INMT (0.44) | — | |
| SCHEMBL810150 | 0.76 | BCHE (0.31) | — | |
| SCHEMBL14777372 | 0.75 | INMT (0.48) | — | |
| SCHEMBL6859068 | 0.71 | INMT (0.39) | — | |
| SCHEMBL10839907 | 0.67 | NOS1 (0.37) | — | |
| SCHEMBL17193579 | 0.67 | USP2 (0.40) | — | |
| SCHEMBL10376372 | 0.66 | ALPL (0.51) | — | |
| SCHEMBL6860529 | 0.65 | INMT (0.47) | — | |
| SCHEMBL10838935 | 0.64 | KDM1A (0.39) | — | |
| SCHEMBL6859941 | 0.64 | INMT (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4465868-A | REACTING CATECHOL AND METHALLYL CHLORIDE IN PRESENCE OF IODIDE CATALYST AND KETONE SOLVENT | OTSUKA KAGAKU YAKUHIN KABUSHIKI KAISHA (JP) | 1984-08-14 | — | — | US | claimed |
| US-4465867-A | REACTING CATECHOL WITH METHALLYL CHLORIDE IN PRESENCE OF POTASSIUM OR SODIUM IODIDE CATALYST | OTSUKA KAGAKU YAKUHIN KABUSHIKI KAISHA (JP) | 1984-08-14 | — | — | US | claimed |
| EP-2785726-B1 | ESTER-FUNCTIONAL SILANES AND THE PREPARATION AND USE THEREOF; AND USE OF IMINIUM COMPOUNDS AS PHASE TRANSFER CATALYSTS | DOW SILICONES CORP (US) | 2018-08-01 | — | — | EP | disclosed |
| EP-2573092-B1 | Method for the preparation and use of bis (alkoxysilylorgano)-dicarboxylates | DOW CORNING (US) | 2017-03-29 | — | — | EP | disclosed |
| US-9518072-B2 | Ester-functional silanes and the preparation and use thereof; and use of iminium compounds as phase transfer catalysts | DOW CORNING CORPORATION (US) | 2016-12-13 | — | — | US | disclosed |
| US-20150126676-A1 | Ester-Functional Silanes And The Preparation And Use Thereof; And Use Of Iminium Compounds As Phase Transfer Catalysts | DOW SILICONES CORPORATION | 2015-05-07 | — | — | US | disclosed |
| EP-2785726-A2 | ESTER-FUNCTIONAL SILANES AND THE PREPARATION AND USE THEREOF; AND USE OF IMINIUM COMPOUNDS AS PHASE TRANSFER CATALYSTS | Dow Corning Corporation (US) | 2014-10-08 | — | — | EP | disclosed |
| US-8580886-B2 | Method for the preparation and use of bis (alkoxysilylorgano)-dicarboxylates | DOW CORNING CORPORATION (US) | 2013-11-12 | — | — | US | disclosed |
| WO-2013081820-A2 | ESTER-FUNCTIONAL SILANES AND THE PREPARATION AND USE THEREOF;AND USE OF IMINIUM COMPOUNDS AS PHASE TRANSFER CATALYSTS | DOW CORNING CORPORATION (US) | 2013-06-06 | — | — | WO | disclosed |
| EP-2573092-A1 | Method for the preparation and use of bis (alkoxysilylorgano)-dicarboxylates | Dow Corning Corporation (US) | 2013-03-27 | — | — | EP | disclosed |
| US-20130072625-A1 | Method for the Preparation and Use of Bis (Alkoxysilylorgano)-Dicarboxylates | DOW CORNING CORPORATION (US) | 2013-03-21 | — | — | US | disclosed |
| US-4465868-A | REACTING CATECHOL AND METHALLYL CHLORIDE IN PRESENCE OF IODIDE CATALYST AND KETONE SOLVENT | OTSUKA KAGAKU YAKUHIN KABUSHIKI KAISHA (JP) | 1984-08-14 | — | — | US | disclosed |
| US-4465867-A | REACTING CATECHOL WITH METHALLYL CHLORIDE IN PRESENCE OF POTASSIUM OR SODIUM IODIDE CATALYST | OTSUKA KAGAKU YAKUHIN KABUSHIKI KAISHA (JP) | 1984-08-14 | — | — | US | disclosed |