Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 13/20 | 0.63 |
| ▸ | HDAC1 | Q13547 | 13/20 | 0.63 |
| ▸ | HDAC2 | Q92769 | 13/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.57 |
| ▸ | NCOR2 | Q9Y618 | 5/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 7/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.47 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3071688 | 0.89 | HDAC3 (0.64) | HDAC3HDAC1HDAC2MAPK1NCOR2 | |
| SCHEMBL31174164 | 0.89 | HDAC3 (0.64) | HDAC3HDAC1HDAC2MAPK1NCOR2 | |
| SCHEMBL9797986 | 0.85 | HDAC3 (0.56) | HDAC3HDAC1HDAC2MAPK1GPR35 | |
| SCHEMBL5697299 | 0.84 | GPR35 (0.68) | GPR35NPC1RAB9APTPN1PTPN11 | |
| SCHEMBL27753436 | 0.83 | HDAC3 (0.58) | HDAC3HDAC1HDAC2MAPK1NCOR2 | |
| SCHEMBL653241 | 0.83 | HDAC3 (0.68) | HDAC3HDAC1HDAC2MAPK1NCOR2 | |
| SCHEMBL250263 | 0.80 | HDAC3 (0.64) | HDAC3HDAC1HDAC2MAPK1NCOR2 | |
| SCHEMBL9515806 | 0.80 | NPC1 (0.67) | HDAC3HDAC1HDAC2MAPK1NCOR2 | |
| SCHEMBL13068319 | 0.80 | HDAC3 (0.55) | HDAC3HDAC1HDAC2MAPK1NCOR2 | |
| SCHEMBL440095 | 0.79 | RAB9A (0.67) | GPR35NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4517357-A | COLORING PAPER | BAYER AKTIENGESELLSCHAFT (DE) | 1985-05-14 | — | — | US | disclosed |
| US-4486348-A | YELLOW COLOR ON PAPER | BAYER AKTIENGESELLSCHAFT (DE) | 1984-12-04 | — | — | US | disclosed |
| US-4128660-A | Anti-allergic aminooxanilic acids and esters | THE UPJOHN COMPANY (US) | 1978-12-05 | — | — | US | disclosed |