Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11044528 | 0.87 | CYP3A4 (0.39) | CYP3A4TDP1 | |
| SCHEMBL10732408 | 0.86 | CYP3A4 (0.32) | CYP3A4TDP1TP53 | |
| SCHEMBL28622549 | 0.78 | CYP3A4 (0.36) | CYP3A4TDP1TP53 | |
| SCHEMBL10709552 | 0.78 | CYP3A4 (0.36) | CYP3A4TDP1 | |
| SCHEMBL10728260 | 0.78 | CYP3A4 (0.36) | CYP3A4TDP1 | |
| SCHEMBL11044338 | 0.78 | CYP3A4 (0.36) | CYP3A4TDP1 | |
| SCHEMBL10727558 | 0.77 | CYP3A4 (0.35) | CYP3A4TDP1 | |
| SCHEMBL10384104 | 0.75 | CYP3A4 (0.33) | CYP3A4TDP1 | |
| SCHEMBL163845 | 0.75 | TDP1 (0.41) | CYP3A4TDP1TP53 | |
| SCHEMBL18653544 | 0.75 | RELA (0.31) | CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4480137-A | ALDEHYDES FROM ALPHA-OLEFINS; HEAT RESISTANCE; CATALYST SELECTIVITY | EXXON RESEARCH & ENGINEERING COMPANY (US) | 1984-10-30 | — | — | US | disclosed |
| US-4454353-A | Trihydrocarbyl silyl substituted alkyl diaryl phosphine transition metal complexes and their use as homogeneous hydroformylation-aldolization catalysts | EXXON RESEARCH AND ENGINEERING CO. (US) | 1984-06-12 | — | — | US | disclosed |
| US-4451673-A | REACTING OLEFINS WITH CARBON MONOXIDE AND HYDROGEN TO YIELD ALDEHYDES | EXXON RESEARCH AND ENGINEERING CO. (US) | 1984-05-29 | — | — | US | disclosed |
| US-4450299-A | ALDEHYDES FROM UNSATURATED ACYCLIC HYDROCARBONS, CARBON MONOXIDE AND HYDROGEN | EXXON RESEARCH AND ENGINEERING CO. (US) | 1984-05-22 | — | — | US | disclosed |