Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10881929 | 0.88 | MEN1 (0.33) | MEN1KMT2ACA1CA2CA9 | |
| SCHEMBL593487 | 0.80 | LMNA (0.47) | LMNACYP2A6MAOBMAOAMEN1 | |
| Hydrochloric Acid SCHEMBL11098692 | 0.78 | LMNA (0.44) | LMNACYP2A6MAOBMAOAMEN1 | |
| SCHEMBL7771305 | 0.78 | LMNA (0.44) | LMNACYP2A6MAOBMAOAMEN1 | |
| SCHEMBL594537 | 0.76 | LMNA (0.42) | LMNACYP2A6MAOBMAOAMEN1 | |
| SCHEMBL5503603 | 0.76 | LMNA (0.42) | LMNACYP2A6MAOBMAOAMEN1 | |
| SCHEMBL991332 | 0.74 | LTA4H (0.45) | MAOAKMT2ACA1CA2CA9 | |
| SCHEMBL11470964 | 0.74 | LMNA (0.40) | LMNACYP2A6MAOBMAOAMEN1 | |
| SCHEMBL7771307 | 0.74 | LMNA (0.40) | LMNACYP2A6MAOBMAOAMEN1 | |
| SCHEMBL7771310 | 0.74 | LMNA (0.40) | LMNACYP2A6MAOBMAOAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018091542-A1 | CYCLIC PHOSPHATE SUBSTITUTED NUCLEOSIDE DERIVATIVES FOR THE TREATMENT OF LIVER DISEASES | IDENIX PHARMACEUTICALS LLC (US) | 2018-05-24 | — | — | WO | disclosed |
| US-4474948-A | Benzazolides and their employment in phosphite ester oligonucleotide synthesis processes | BIOSEARCH (US) | 1984-10-02 | — | — | US | disclosed |
| US-4187385-A | TITANIUM COMPONENT COPULVERIZED WITH ORGANOALUMINUM COMPOUND AND ETHYLENE OR A-OLEFINS, PARTICLE SIZE | MITSUI TOATSU CHEMICAL, INC. (JP) | 1980-02-05 | — | — | US | disclosed |
| US-4028481-A | ACTIVATED TITANIUM TRICHLORIDE AND AN ORGANOALUMINUM COMPOUND | MITSUI TOATSU CHEMICALS, INCORPORATED (JA) | 1977-06-07 | — | — | US | disclosed |
| US-4000239-A | PROCESS FOR SPINNING NAPHTHALATE POLYESTER FIBERS | TEIJIN LIMITED (JA) | 1976-12-28 | — | — | US | disclosed |