SCHEMBL11470964

SCHEMBL11470964

ClOP(OCl)Oc1ccc(Cl)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.40
CYP2A6 P11509 1/20 0.40
MAOB P27338 4/20 0.39
MAOA P21397 1/20 0.39
MEN1 O00255 3/20 0.37
KMT2A Q03164 3/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA9 Q16790 1/20 0.37
APP P05067 1/20 0.36
HPGD P15428 2/20 0.33
CYP1A2 P05177 3/20 0.32
CYP2C19 P33261 3/20 0.32
CYP2D6 P10635 2/20 0.32
MAPT P10636 2/20 0.32
CYP2C9 P11712 2/20 0.32
CYP3A4 P08684 1/20 0.32
PPARA Q07869 1/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL593487 0.87 LMNA (0.47) LMNACYP2A6MAOBMAOAMEN1
SCHEMBL7771305 0.84 LMNA (0.44) LMNACYP2A6MAOBMAOAMEN1
Hydrochloric Acid SCHEMBL11098692 0.84 LMNA (0.44) LMNACYP2A6MAOBMAOAMEN1
SCHEMBL11478152 0.78 ACHE (0.44) LMNAMEN1KMT2ACA1CA2
SCHEMBL10491036 0.78 HPGD (0.41) LMNACYP2A6MAOBMAOAMEN1
SCHEMBL8768246 0.78 TSHR (0.46) LMNACYP2A6MAOBMAOAMEN1
SCHEMBL2497300 0.77 TSHR (0.41) LMNAMAOAKMT2ACA1CA2
SCHEMBL5318307 0.77 LTA4H (0.41) MAOAKMT2ACA1CA2CA9
SCHEMBL11437986 0.76 MAOA (0.37) LMNACYP2A6MAOBMAOAMEN1
SCHEMBL11503476 0.76 HPGD (0.53) MAOBMAOAMEN1KMT2ACA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4187385-A TITANIUM COMPONENT COPULVERIZED WITH ORGANOALUMINUM COMPOUND AND ETHYLENE OR A-OLEFINS, PARTICLE SIZE MITSUI TOATSU CHEMICAL, INC. (JP) 1980-02-05 US disclosed
US-4028481-A ACTIVATED TITANIUM TRICHLORIDE AND AN ORGANOALUMINUM COMPOUND MITSUI TOATSU CHEMICALS, INCORPORATED (JA) 1977-06-07 US disclosed
US-4000239-A PROCESS FOR SPINNING NAPHTHALATE POLYESTER FIBERS TEIJIN LIMITED (JA) 1976-12-28 US disclosed