Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9417632 | 0.86 | ERN1 (0.57) | ERN1MEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL11048252 | 0.83 | MEN1 (0.40) | ERN1MEN1KMT2AUSP2KEAP1 | |
| SCHEMBL11551067 | 0.81 | TDP1 (0.52) | MEN1KMT2AUSP2KEAP1NFE2L2 | |
| SCHEMBL3390153 | 0.81 | TDP1 (0.52) | MEN1KMT2AUSP2KEAP1NFE2L2 | |
| Hydrochloric Acid SCHEMBL5914596 | 0.79 | TDP1 (0.50) | MEN1KMT2AUSP2KEAP1NFE2L2 | |
| SCHEMBL21685403 | 0.79 | ALDH1A1 (0.40) | ERN1MEN1KMT2AUSP2KEAP1 | |
| SCHEMBL28586114 | 0.79 | MEN1 (0.37) | ERN1MEN1KMT2AUSP2KEAP1 | |
| SCHEMBL196088 | 0.78 | ERN1 (0.65) | ERN1MEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL2841960 | 0.78 | ERN1 (0.50) | ERN1MEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL27985682 | 0.78 | ERN1 (0.50) | ERN1MEN1KMT2AALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |