SCHEMBL1104835

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13030954	0.81	HTT (0.79)	MAPK1HTTTSHRALDH1A1NR1H2
	SCHEMBL17694823	0.81	MAPK1 (0.67)	MAPK1HTTTSHRCYP1A2ALDH1A1
	SCHEMBL19275970	0.79	MAPK1 (0.65)	MAPK1HTTTSHRALDH1A1NR1H2
	SCHEMBL10041256	0.78	MAPK1 (0.79)	MAPK1HTTTSHRCYP1A2ALDH1A1
	SCHEMBL540947	0.78	MAPK1 (1.00)	MAPK1HTTTSHRALDH1A1NR1H2
	SCHEMBL13052926	0.76	HTT (0.69)	MAPK1HTTTSHRALDH1A1NR1H2
	SCHEMBL7760076	0.75	MAPK1 (0.79)	MAPK1HTTTSHRALDH1A1NR1H2
	SCHEMBL13080878	0.74	TSHR (0.73)	MAPK1HTTTSHRALDH1A1NR1H2
	SCHEMBL19275967	0.74	MAPK1 (0.72)	MAPK1HTTTSHRALDH1A1NR1H2
	SCHEMBL22507480	0.74	HTT (0.67)	MAPK1HTTTSHRALDH1A1NR1H2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 171 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.