SCHEMBL1104840

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL24295110	0.87	ATM (0.60)	ATMMEN1KMT2AHDAC1HDAC8
	SCHEMBL2094091	0.87	ATM (0.50)	ATMMEN1KMT2AHDAC1HDAC8
	SCHEMBL18999494	0.85	HDAC1 (0.46)	ATMMEN1KMT2AHDAC1HDAC8
	SCHEMBL822540	0.84	KDM4E (0.66)	ATMMEN1KMT2AHDAC1HDAC8
	SCHEMBL22969893	0.81	ESR1 (0.53)	ATMMEN1KMT2AHDAC1HDAC8
	SCHEMBL30060553	0.81	ATM (0.54)	ATMMEN1KMT2AHDAC1HDAC8
	SCHEMBL28395012	0.81	ATM (0.54)	ATMMEN1KMT2AHDAC1HDAC8
	SCHEMBL1104827	0.81	PDE10A (0.59)	ATMMEN1KMT2AHDAC1HDAC8
	SCHEMBL1104822	0.79	ATM (0.55)	ATMMEN1KMT2AHDAC1HDAC8
	SCHEMBL1104828	0.79	HDAC1 (0.64)	ATMMEN1KMT2AHDAC1HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.