Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.54 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31011703 | 0.89 | KDM4E (0.57) | KDM4EALDH1A1KCNJ1LMNAMAPT | |
| SCHEMBL11045600 | 0.85 | PLA2G2A (0.56) | KDM4EALDH1A1KCNJ1LMNAMAPT | |
| SCHEMBL30109416 | 0.84 | KDM4E (0.49) | KDM4EALDH1A1KCNJ1LMNAMAPT | |
| SCHEMBL29283174 | 0.81 | ALDH1A1 (0.61) | KDM4EALDH1A1KCNJ1LMNAMAPT | |
| SCHEMBL4572872 | 0.80 | L3MBTL1 (0.58) | KDM4EALDH1A1KCNJ1LMNAMAPT | |
| SCHEMBL5625428 | 0.80 | L3MBTL1 (0.62) | KDM4EALDH1A1KCNJ1LMNAMAPT | |
| SCHEMBL23728268 | 0.80 | KDM4E (0.48) | KDM4EALDH1A1KCNJ1LMNAMAPT | |
| SCHEMBL9511103 | 0.79 | KDM4E (0.57) | KDM4EALDH1A1KCNJ1LMNAMAPT | |
| SCHEMBL260552 | 0.79 | KCNJ1 (0.56) | KDM4EALDH1A1KCNJ1LMNAMAPT | |
| SCHEMBL27784071 | 0.79 | L3MBTL1 (0.65) | KDM4EALDH1A1KCNJ1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4477666-A | ANTICARCINO GENIC AGENTS | TOYAMA CHEMICAL CO., LTD. (JP) | 1984-10-16 | — | — | US | disclosed |
| US-4477664-A | CARCINOSTATIC ACTIVITY, LOW TOXICITY, INTERMEDIATES | TOYAMA CHEMICAL CO., LTD. (JP) | 1984-10-16 | — | — | US | disclosed |
| US-4460774-A | ANTICARCINOGENIC AGENTS | TOYAMA CHEMICAL COMPANY, LIMITED (JP) | 1984-07-17 | — | — | US | disclosed |
| US-4448963-A | ANTICARCINOGENS | TOYAMA CHEMICAL CO., LTD. (JP) | 1984-05-15 | — | — | US | disclosed |
| US-4436921-A | CARCINOSTATIC ACTIVITY | TOYAMA CHEMICAL CO., LTD. (JP) | 1984-03-13 | — | — | US | disclosed |