Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9514131 | 0.80 | ALDH1A1 (0.60) | KDM4EALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL31011703 | 0.79 | KDM4E (0.57) | KDM4EALDH1A1KCNJ1MAPTLMNA | |
| SCHEMBL11048969 | 0.79 | KDM4E (0.57) | KDM4EALDH1A1KCNJ1MAPTLMNA | |
| SCHEMBL28958322 | 0.78 | ALDH1A1 (0.50) | KDM4EALDH1A1SMN1; SMN2POLBKMT2A | |
| SCHEMBL9511632 | 0.78 | HTT (0.59) | KDM4EALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL10894937 | 0.77 | MEN1 (0.60) | KDM4EALDH1A1KCNJ1MAPTLMNA | |
| SCHEMBL10894942 | 0.77 | MEN1 (0.60) | KDM4EALDH1A1KCNJ1MAPTLMNA | |
| SCHEMBL4182979 | 0.77 | MAPK1 (0.57) | KDM4EALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL29283174 | 0.75 | ALDH1A1 (0.61) | KDM4EALDH1A1KCNJ1MAPTLMNA | |
| SCHEMBL9743824 | 0.74 | ALDH1A1 (0.44) | ALDH1A1KCNJ1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0320910-B1 | 2-Thiazolidinone derivatives, pharmaceutical compositions containing them, process for preparing same, and use | RICHTER GEDEON VEGYESZET (HU) | 1993-12-08 | — | — | EP | claimed |
| EP-0320910-B1 | 2-Thiazolidinone derivatives, pharmaceutical compositions containing them, process for preparing same, and use | RICHTER GEDEON VEGYESZET (HU) | 1993-12-08 | — | — | EP | disclosed |
| US-4937252-A | 2-thiazolidinone derivatives, pharmaceutical compositions containing them and process for preparing same | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1990-06-26 | — | — | US | disclosed |
| EP-0320910-A1 | 2-Thiazolidinone derivatives, pharmaceutical compositions containing them, process for preparing same, and use | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1989-06-21 | — | — | EP | disclosed |