SCHEMBL11049067

SCHEMBL11049067

C=CCC1COC(c2ccc(C(=O)Cl)cc2)OC1

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9362547 0.87 ALDH1A1 (0.37) NPC1RAB9ASMN1; SMN2MAPK1
Hydrochloric Acid SCHEMBL11050519 0.86 ALDH1A1 (0.36) NPC1RAB9ASMN1; SMN2MAPK1
SCHEMBL9879624 0.82 RAB9A (0.56) NPC1RAB9ASMN1; SMN2
SCHEMBL9879622 0.82 RAB9A (0.56) NPC1RAB9ASMN1; SMN2
SCHEMBL10942155 0.80 APAF1 (0.39)
SCHEMBL10869428 0.77
SCHEMBL9617137 0.77 CYP2C9 (0.44) MAPK1
SCHEMBL9340714 0.77 CYP2C9 (0.44) MAPK1
SCHEMBL11093051 0.76 ALDH1A1 (0.36) SMN1; SMN2
SCHEMBL10973103 0.75 THRA (0.40) NPC1RAB9ASMN1; SMN2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-59098079-A None JP disclosed
JP-59082382-A None JP disclosed
JP-S5998079-A M-HALOGEN-SUBSTITUTED METADIOXANE ESTER CHISSO CORP 1984-06-06 JP disclosed
JP-S5982382-A M-DIOXANE ESTER CONTAINING HALOGEN CHISSO CORP 1984-05-12 JP disclosed