Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11006723 | 0.87 | ALDH1A1 (0.50) | KMT2ASRD5A2MAPK1HPGDCES2 | |
| SCHEMBL11052447 | 0.84 | LTA4H (0.40) | KMT2AMAPK1HPGDCES2CES1 | |
| SCHEMBL11042726 | 0.77 | SRD5A2 (0.44) | KMT2ASRD5A2MAPK1HPGDCES2 | |
| SCHEMBL11044558 | 0.73 | MAP2K1 (0.40) | KMT2AHPGDALOX15TSHRPOLB | |
| SCHEMBL11181578 | 0.70 | PDE4A (0.67) | KMT2ASRD5A2MAPK1HPGDCES2 | |
| SCHEMBL2915910 | 0.69 | GPR35 (0.46) | KMT2AHPGDALOX15TSHRPOLB | |
| SCHEMBL9787361 | 0.69 | PDE4A (0.45) | KMT2ASRD5A2MAPK1HPGDCES2 | |
| SCHEMBL8604431 | 0.69 | MAPT (0.46) | KMT2ASRD5A2HPGDNPSR1PTGS2 | |
| SCHEMBL7678013 | 0.68 | HPGD (0.45) | SRD5A2MAPK1HPGDALOX15TSHR | |
| SCHEMBL11052444 | 0.68 | SRD5A2 (0.46) | KMT2ASRD5A2MAPK1HPGDCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4456759-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIPYRETICS, ANTICOAGULANTS, AND MUSCLE RELAXANTS | SYNTEX (U.S.A.) INC. (US) | 1984-06-26 | — | — | US | disclosed |
| US-4347185-A | DECARBOXYLATION OF THE 1,1-DICARBOXYLATES | SYNTEX (U.S.A.) INC. (US) | 1982-08-31 | — | — | US | disclosed |