SCHEMBL11049290

SCHEMBL11049290

CCCC(C(CC)C(=O)O)C(CC)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HKDC1 Q2TB90 1/20 0.42
MME P08473 2/20 0.41
LMNA P02545 3/20 0.40
HSD17B10 Q99714 1/20 0.40
SLC6A3 Q01959 2/20 0.38
CHRM1 P11229 1/20 0.38
AKR1A1 P14550 1/20 0.38
CHRM3 P20309 1/20 0.38
HTR2A P28223 1/20 0.38
HTR2C P28335 1/20 0.38
ADRA1A P35348 1/20 0.38
HRH1 P35367 1/20 0.38
DRD3 P35462 1/20 0.38
HDAC1 Q13547 1/20 0.38
HDAC2 Q92769 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
AOC3 Q16853 1/20 0.38
TRPM8 Q7Z2W7 1/20 0.38
CYP2D6 P10635 2/20 0.37
CYP1A2 P05177 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1083717 0.83 HKDC1 (0.50) HKDC1MMELMNAHSD17B10SLC6A3
SCHEMBL28382136 0.81 HKDC1 (0.42) HKDC1LMNAHSD17B10TDP1AOC3
SCHEMBL1131423 0.80 POLB (0.49) HKDC1MMECYP3A4POLBMEN1
SCHEMBL11050985 0.78 HKDC1 (0.46) HKDC1MMELMNAHSD17B10CYP2D6
SCHEMBL13763093 0.77 HKDC1 (0.45) HKDC1MMELMNAHSD17B10CYP2D6
SCHEMBL11042480 0.76 LMNA (0.44) HKDC1MMELMNAHSD17B10CYP2D6
SCHEMBL28035948 0.75 CHRM1 (0.50) SLC6A3CHRM1AKR1A1CHRM3HTR2A
SCHEMBL7668203 0.75 HKDC1 (0.46) HKDC1MMELMNAHSD17B10HDAC1
SCHEMBL28378824 0.73 HKDC1 (0.45) HKDC1LMNAHSD17B10TDP1CYP2D6
SCHEMBL28053710 0.73 PDPK1 (0.43) MMELMNASLC6A3AOC3CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4464290-A REMOVAL OF CONIFERYL BENZOATE AND ACETATE SHISEIDO COMPANY LTD. (JP) 1984-08-07 US disclosed