SCHEMBL28382136

SCHEMBL28382136

CCCC(C(CC)c1ccccc1)C(CCC(=O)O)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HKDC1 Q2TB90 1/20 0.42
LMNA P02545 4/20 0.41
HSD17B10 Q99714 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
CYSLTR2 Q9NS75 1/20 0.40
CYSLTR1 Q9Y271 1/20 0.40
ALDH1A1 P00352 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2D6 P10635 1/20 0.40
TSHR P16473 1/20 0.40
CYP2C19 P33261 1/20 0.40
NAALAD2 Q9Y3Q0 1/20 0.39
CPA3 P15088 1/20 0.39
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
AOC3 Q16853 1/20 0.38
NR4A2 P43354 1/20 0.38
POLB P06746 2/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28378824 0.90 HKDC1 (0.45) HKDC1LMNAHSD17B10TDP1ALDH1A1
SCHEMBL11049290 0.81 HKDC1 (0.42) HKDC1LMNAHSD17B10TDP1CYP1A2
SCHEMBL27580075 0.78 MEN1 (0.44) HKDC1LMNAHSD17B10TDP1ALDH1A1
SCHEMBL8849672 0.77 HKDC1 (0.42) HKDC1LMNAHSD17B10TDP1ALDH1A1
SCHEMBL28381979 0.77 HKDC1 (0.42) HKDC1LMNAHSD17B10TDP1ALDH1A1
SCHEMBL8904725 0.76 HDAC3 (0.47) LMNAHSD17B10TDP1CYSLTR2CYSLTR1
SCHEMBL26269478 0.75 TAAR1 (0.53) ALDH1A1CYP1A2CYP2D6TSHRCYP2C19
SCHEMBL3056333 0.74 GABBR2 (0.47) LMNAHSD17B10CYSLTR2CYSLTR1ALDH1A1
SCHEMBL7051893 0.74 ACE (0.40) HKDC1LMNAHSD17B10TDP1ALDH1A1
SCHEMBL27305718 0.73 CYP2C19 (0.48) LMNAHSD17B10TDP1ALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107868152-B Catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2020-09-15 CN claimed
CN-107868153-B Catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2020-07-24 CN claimed
CN-110950984-B Catalyst component for olefin polymerization, catalyst and olefin polymerization method 中国石油化工股份有限公司 2021-11-19 CN disclosed
CN-107868152-B Catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2020-09-15 CN disclosed
CN-107868153-B Catalyst component for olefin polymerization, catalyst and application thereof 中国石油化工股份有限公司 2020-07-24 CN disclosed
CN-110950984-A Catalyst component for olefin polymerization, catalyst and olefin polymerization method 中国石油化工股份有限公司 2020-04-03 CN disclosed