Naphthalene

Naphthalene

SCHEMBL11049568

O=C(c1ccccc1)c1cccc(-c2ccccc2)c1-c1ccccc1.c1ccc2ccccc2c1

nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.51
HNF4A P41235 1/20 0.50
AKR1C3 P42330 1/20 0.47
MEN1 O00255 4/20 0.47
KMT2A Q03164 4/20 0.47
MAPT P10636 3/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
MAPK1 P28482 1/20 0.47
ATM Q13315 2/20 0.46
CDC25B P30305 1/20 0.46
MAPK13 O15264 1/20 0.46
MAPK12 P53778 1/20 0.46
MAPK11 Q15759 1/20 0.46
MAPK14 Q16539 1/20 0.46
GAA P10253 1/20 0.44
BCAT2 O15382 1/20 0.44
L3MBTL1 Q9Y468 3/20 0.44
NPSR1 Q6W5P4 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
HTT P42858 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2333980 0.95 ALDH1A1 (0.56) ALDH1A1HNF4AAKR1C3MEN1KMT2A
SCHEMBL30618783 0.95 ALDH1A1 (0.56) ALDH1A1HNF4AAKR1C3MEN1KMT2A
SCHEMBL8778491 0.86 HNF4A (0.60) ALDH1A1HNF4AMEN1KMT2AMAPT
SCHEMBL9065832 0.85 KMT2A (0.56) ALDH1A1HNF4AAKR1C3MEN1KMT2A
SCHEMBL1666410 0.84 ALDH1A1 (0.56) ALDH1A1HNF4AAKR1C3MEN1KMT2A
SCHEMBL934810 0.84 AKR1C3 (0.59) ALDH1A1HNF4AAKR1C3MAPTATM
Ethane SCHEMBL11390240 0.83 KMT2A (0.53) ALDH1A1HNF4AAKR1C3MEN1KMT2A
SCHEMBL30370112 0.82 MEN1 (0.41) ALDH1A1HNF4AAKR1C3MEN1KMT2A
SCHEMBL6034374 0.81 HNF4A (0.70) ALDH1A1HNF4AAKR1C3MAPTMAPK1
SCHEMBL27514569 0.81 ALDH1A1 (0.56) ALDH1A1HNF4AAKR1C3MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4473484-A PHOTOISOMERIZABLE MATERIAL, PHOTOSENSITIZER, AND BY-PRODUCT INHIBITOR AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY (JP) 1984-09-25 US disclosed