SCHEMBL9065832

SCHEMBL9065832

O=C(c1ccccc1)c1cccc(-c2ccc(O)cc2)c1-c1ccc(O)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.56
MAPT P10636 3/20 0.56
MEN1 O00255 2/20 0.56
LMNA P02545 2/20 0.56
RAB9A P51151 1/20 0.56
MMP2 P08253 1/20 0.50
MMP3 P08254 1/20 0.50
LIG1 P18858 1/20 0.50
HNF4A P41235 1/20 0.49
MMP9 P14780 1/20 0.48
GAA P10253 2/20 0.47
USP2 O75604 1/20 0.47
KEAP1 Q14145 1/20 0.47
NFE2L2 Q16236 1/20 0.47
PTPN1 P18031 2/20 0.47
ALDH1A1 P00352 2/20 0.46
AKR1C3 P42330 1/20 0.46
CDC25B P30305 1/20 0.45
ATM Q13315 1/20 0.45
CES2 O00748 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethane SCHEMBL11390240 0.97 KMT2A (0.53) KMT2AMAPTMEN1LMNARAB9A
SCHEMBL30618783 0.90 ALDH1A1 (0.56) KMT2AMAPTMEN1LMNAHNF4A
SCHEMBL2333980 0.90 ALDH1A1 (0.56) KMT2AMAPTMEN1LMNAHNF4A
SCHEMBL7167624 0.86 MAPT (0.63) KMT2AMAPTMEN1LMNARAB9A
Naphthalene SCHEMBL11049568 0.85 ALDH1A1 (0.51) KMT2AMAPTMEN1LMNAHNF4A
SCHEMBL8714557 0.83 HNF4A (0.59) KMT2AMAPTLMNAMMP2MMP3
SCHEMBL8778491 0.81 HNF4A (0.60) KMT2AMAPTMEN1LMNAHNF4A
SCHEMBL29091120 0.80 HNF4A (0.61) KMT2AMAPTMEN1LMNARAB9A
SCHEMBL6034374 0.80 HNF4A (0.70) MAPTHNF4AGAAPTPN1ALDH1A1
SCHEMBL1666410 0.80 ALDH1A1 (0.56) KMT2AMAPTMEN1LMNAHNF4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111684013-B Thermoplastic resin composition and molded article thereof 帝人株式会社 2023-02-28 CN disclosed
WO-2022086231-A1 POLYCARBONATE COMPOSITION AND MOLDED ARTICLES THEREOF 주식회사 엘지화학 2022-04-28 WO disclosed
EP-0342027-B1 Epoxy-aromatic polysiloxane compositions NAT STARCH CHEM INVEST (US) 1996-01-24 EP disclosed
US-5049627-A Epoxy-aromatic polysiloxane compositions INVESTMENT HOLDING CORPORATION (US) 1991-09-17 US disclosed
EP-0342027-A2 Epoxy-aromatic polysiloxane compositions NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 1989-11-15 EP disclosed
EP-0309190-A2 Polyimide coating compositions NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 1989-03-29 EP disclosed