SCHEMBL1666410

SCHEMBL1666410

O=C(c1ccccc1)c1cccc(C(=O)c2ccccc2)c1-c1ccccc1-c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.56
HNF4A P41235 1/20 0.55
AKR1C3 P42330 1/20 0.52
ATM Q13315 2/20 0.50
CDC25B P30305 2/20 0.50
MAPK13 O15264 1/20 0.49
MAPK12 P53778 1/20 0.49
MAPK11 Q15759 1/20 0.49
MAPK14 Q16539 1/20 0.49
MAPT P10636 3/20 0.48
GAA P10253 1/20 0.48
BCAT2 O15382 1/20 0.48
CHRNB2 P17787 1/20 0.47
CHRNB4 P30926 1/20 0.47
CHRNA3 P32297 1/20 0.47
CHRNA4 P43681 1/20 0.47
ADORA1 P30542 1/20 0.46
L3MBTL1 Q9Y468 2/20 0.45
TDP1 Q9NUW8 2/20 0.45
MEN1 O00255 4/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2333980 0.89 ALDH1A1 (0.56) ALDH1A1HNF4AAKR1C3ATMCDC25B
SCHEMBL30618783 0.89 ALDH1A1 (0.56) ALDH1A1HNF4AAKR1C3ATMCDC25B
SCHEMBL1666496 0.86 ALDH1A1 (0.53) ALDH1A1HNF4AAKR1C3ATMCDC25B
SCHEMBL6034374 0.85 HNF4A (0.70) ALDH1A1HNF4AAKR1C3ATMCDC25B
SCHEMBL27716367 0.85 ALDH1A1 (0.59) ALDH1A1HNF4AAKR1C3ATMCDC25B
Naphthalene SCHEMBL11049568 0.84 ALDH1A1 (0.51) ALDH1A1HNF4AAKR1C3ATMCDC25B
SCHEMBL934810 0.84 AKR1C3 (0.59) ALDH1A1HNF4AAKR1C3ATMCDC25B
SCHEMBL472751 0.84 ALDH1A1 (0.63) ALDH1A1HNF4AAKR1C3ATMCDC25B
Hydrogen Sulfide SCHEMBL27800862 0.83 ALDH1A1 (0.58) ALDH1A1HNF4AAKR1C3ATMCDC25B
SCHEMBL301948 0.83 ALDH1A1 (0.58) ALDH1A1HNF4AAKR1C3ATMCDC25B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1830228-B1 COMPOUND FOR RESIST AND RADIATION-SENSITIVE COMPOSITION MITSUBISHI GAS CHEMICAL CO (JP) 2015-08-05 EP disclosed
EP-2808736-A2 Compound for resist and radiation-sensitive composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2014-12-03 EP disclosed
US-8802353-B2 Compound for resist and radiation-sensitive composition specification MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2014-08-12 US disclosed
EP-2662727-A2 Compound for resist and radiation-sensitive composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2013-11-13 EP disclosed
US-8350096-B2 Compound for resist and radiation-sensitive composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2013-01-08 US disclosed
US-20130004896-A1 COMPOUND FOR RESIST AND RADIATION-SENSITIVE COMPOSITION SPECIFICATION ECHIGO MASATOSHI (JP) 2013-01-03 US disclosed
US-20110165516-A1 COMPOUND FOR RESIST AND RADIATION-SENSITIVE COMPOSITION ECHIGO MASATOSHI 2011-07-07 US disclosed
US-7919223-B2 Polyphenol compound synthesized by condensation between aromatic ketone or aldehyde and a phenol; acid-amplified, non-polymeric resist; highly sensitive to KrF excimer lasers, extreme ultraviolet rays, electron beams, X-rays; resist patterns with high resolution, high heat, etch resistance MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2011-04-05 US disclosed
US-20080113294-A1 Compound for Resist and Radiation-Sensitive Composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2008-05-15 US disclosed
EP-1830228-A1 COMPOUND FOR RESIST AND RADIATION-SENSITIVE COMPOSITION MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2007-09-05 EP disclosed
US-5171506-A Melt spinning TOYO BOSEKI KABUSHIKI KAISHA (JP) 1992-12-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110165516-A1 COMPOUND FOR RESIST AND RADIATION-SENSITIVE COMPOSITION XRCC6, XRCC5, KISS1R ALDH1A1 1170/4885HNF4A 1268/4885AKR1C3 782/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.