Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | MPC2 | O95563 | 1/20 | 0.35 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11049864 | 0.79 | MAPK1 (0.49) | GCKPARP1HDAC6TDP1ALDH1A1 | |
| SCHEMBL11059897 | 0.70 | KDM4E (0.56) | HDAC6TDP1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL11045319 | 0.70 | KDM4E (0.56) | HDAC6TDP1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL11059198 | 0.70 | CHRM2 (0.43) | ALDH1A1POLBLMNACYP1A2CYP3A4 | |
| SCHEMBL11045604 | 0.69 | SMN1; SMN2 (0.41) | GCKHDAC6TDP1SMN1; SMN2POLB | |
| SCHEMBL1698854 | 0.67 | GPR119 (0.57) | ALDH1A1KDM4ELMNAMAPTPKM | |
| SCHEMBL27975171 | 0.67 | VNN1 (0.44) | CSF1RFLT3TDP1ALDH1A1MEN1 | |
| SCHEMBL24798653 | 0.67 | LTA4H (0.37) | GCKHDAC6TDP1TRPA1SMN1; SMN2 | |
| SCHEMBL24501221 | 0.66 | MAPK1 (0.49) | CSF1RFLT3CYP2C9PARP1TDP1 | |
| SCHEMBL11061422 | 0.66 | P4HTM (0.59) | TDP1ALDH1A1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1984004302-A1 | SUBSTITUTED PICOLINIC ACIDS, PROCESSES FOR THEIR PREPARATION, THEIR USE AND MEDICAMENTS CONTAINING THEM | BYK GULDEN LOMBERG CHEM FAB (DE) | 1984-11-08 | — | — | WO | disclosed |