Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCEH1 | Q6PIU2 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | STAT1 | P42224 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11053906 | 0.87 | NCEH1 (0.43) | NCEH1MEN1KMT2AL3MBTL1LMNA | |
| SCHEMBL11057263 | 0.86 | NCEH1 (0.46) | NCEH1MEN1KMT2AL3MBTL1LMNA | |
| SCHEMBL11056745 | 0.80 | SLC9A1 (0.45) | NCEH1CYP1A2POLBNPC1RAB9A | |
| SCHEMBL11167863 | 0.79 | AKR1B10 (0.43) | NCEH1MEN1KMT2AL3MBTL1LMNA | |
| SCHEMBL9380765 | 0.76 | NCEH1 (0.47) | NCEH1MEN1KMT2AL3MBTL1LMNA | |
| SCHEMBL11161627 | 0.74 | ACP1 (0.37) | NCEH1MEN1KMT2ACYP1A2RXFP1 | |
| SCHEMBL192728 | 0.74 | NCEH1 (0.54) | NCEH1MEN1KMT2AL3MBTL1LMNA | |
| SCHEMBL11668971 | 0.74 | ALDH1A1 (0.43) | MEN1KMT2AL3MBTL1LMNACYP1A2 | |
| SCHEMBL181238 | 0.73 | PLAU (0.61) | NCEH1LMNAATMPLAUSMN1; SMN2 | |
| SCHEMBL30369699 | 0.73 | PLAU (0.61) | NCEH1LMNAATMPLAUSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447452-A | ANTIDIABETIC AGENT | AYERST, MCKENNA & HARRISON INC. (CA) | 1984-05-08 | — | — | US | disclosed |