Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | CAD | P27708 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11051394 | 0.80 | SMN1; SMN2 (0.36) | ALOX15ALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL28160177 | 0.80 | ALDH1A1 (0.44) | ALOX15ALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL8307598 | 0.80 | ALDH1A1 (0.41) | ALOX15ALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL6809972 | 0.80 | ALDH1A1 (0.53) | ALOX15ALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL6806491 | 0.80 | ALDH1A1 (0.53) | ALOX15ALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL8308112 | 0.80 | ALDH1A1 (0.53) | ALOX15ALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL7521267 | 0.77 | ALOX15 (0.50) | ALOX15ALDH1A1TDP1HSD17B10CAD | |
| SCHEMBL10972712 | 0.77 | — | — | |
| SCHEMBL11050300 | 0.77 | ALDH1A1 (0.39) | ALOX15ALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL11147040 | 0.77 | ALDH1A1 (0.41) | ALOX15ALDH1A1CYP3A4TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4465844-A | PEPTIDE, GERMICIDE, DISINFECTANT | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1984-08-14 | — | — | US | disclosed |
| US-4436918-A | FROM A 2,5-DIOXOPYRROLIDINE COMPOUND | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1984-03-13 | — | — | US | disclosed |