SCHEMBL8307598

SCHEMBL8307598

CCOC(=O)C(Cl)CC(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.41
ALOX15 P16050 4/20 0.41
CYP3A4 P08684 2/20 0.41
TSHR P16473 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
HSD17B10 Q99714 2/20 0.40
CHRM1 P11229 1/20 0.40
ADORA1 P30542 1/20 0.40
MEN1 O00255 1/20 0.39
NPC1 O15118 1/20 0.39
KMT2A Q03164 1/20 0.39
LMNA P02545 1/20 0.39
MGAM O43451 1/20 0.37
GAA P10253 1/20 0.37
SI P14410 1/20 0.37
MGAM2 Q2M2H8 1/20 0.37
SOAT1 P35610 1/20 0.37
CYP2D6 P10635 2/20 0.36
EGLN1 Q9GZT9 1/20 0.36
PIN1 Q13526 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1648718 0.83 SLC22A6 (0.39) ALOX15TSHRTDP1LMNAMAPT
SCHEMBL6806491 0.82 ALDH1A1 (0.53) ALDH1A1ALOX15CYP3A4TSHRTDP1
SCHEMBL28160177 0.82 ALDH1A1 (0.44) ALDH1A1ALOX15CYP3A4TSHRTDP1
SCHEMBL8308112 0.82 ALDH1A1 (0.53) ALDH1A1ALOX15CYP3A4TSHRTDP1
SCHEMBL6809972 0.82 ALDH1A1 (0.53) ALDH1A1ALOX15CYP3A4TSHRTDP1
SCHEMBL11050299 0.80 ALOX15 (0.46) ALDH1A1ALOX15CYP3A4TSHRTDP1
SCHEMBL6057628 0.79 KMT2A (0.37) ALOX15TSHRTDP1KMT2ALMNA
SCHEMBL1480202 0.79 KMT2A (0.37) ALOX15TSHRTDP1KMT2ALMNA
SCHEMBL11050300 0.78 ALDH1A1 (0.39) ALDH1A1ALOX15CYP3A4TSHRTDP1
SCHEMBL11147040 0.78 ALDH1A1 (0.41) ALDH1A1ALOX15CYP3A4TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260108617-A1 AUTO-TUNING DRUG REGULATOR CONSTRUCTIONS RETHINK64 BIONETWORKS PBC (US) 2026-04-23 US disclosed
WO-2024155707-A1 AUTO-TUNING DRUG REGULATOR CONSTRUCTIONS RETHINK64 BIONETWORKS PBC (US) 2024-07-25 WO disclosed
EP-0758312-B1 SUBSTITUTED FUSED AND BRIDGED BICYCLIC COMPOUNDS AS THERAPEUTIC AGENTS LILLY CO ELI (US) 1999-12-22 EP disclosed
EP-0946515-A1 PARASITICIDAL PYRAZOLES Pfizer Limited (GB) 1999-10-06 EP disclosed
WO-1998024767-A1 PARASITICIDAL PYRAZOLES PFIZER LIMITED (GB) 1998-06-11 WO disclosed
EP-0758312-A4 SUBSTITUTED FUSED AND BRIDGED BICYCLIC COMPOUNDS AS THERAPEUTIC AGENTS LILLY CO ELI (US) 1997-09-10 EP disclosed
EP-0758312-A1 SUBSTITUTED FUSED AND BRIDGED BICYCLIC COMPOUNDS AS THERAPEUTIC AGENTS ELI LILLY AND COMPANY (US) 1997-02-19 EP disclosed
US-5583221-A ANTIINFLAMMATORY AGENTS, CARDIOVASCULAR DISORDERS, VIRICIDES, FUNGICIDES ELI LILLY AND COMPANY (US) 1996-12-10 US disclosed
WO-1996005729-A1 VICINAL-SUBSTITUTED CARBOCYCLIC COMPOUNDS AS THERAPEUTIC AGENTS ELI LILLY AND COMPANY (US) 1996-02-29 WO disclosed
EP-0687249-A1 BALANOIDS ELI LILLY AND COMPANY (US) 1995-12-20 EP disclosed
WO-1995030640-A1 SUBSTITUTED FUSED AND BRIDGED BICYCLIC COMPOUNDS AS THERAPEUTIC AGENTS ELI LILLY AND COMPANY (US) 1995-11-16 WO disclosed
US-5432198-A Enzyme inhibitors SPHINX PHARMACEUTICALS CORPORATION (US) 1995-07-11 US disclosed
WO-1994020062-A2 BALANOIDS AS PROTEIN KINASE C INHIBITORS ELI LILLY AND COMPANY (US) 1994-09-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260108617-A1 AUTO-TUNING DRUG REGULATOR CONSTRUCTIONS TPMT, CYP2D6, ACHE ALDH1A1 1207/4885ALOX15 3079/4885CYP3A4 28/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.