Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | ACP3 | P15309 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7493410 | 0.85 | CYP1A1 (0.48) | MAOBKMT2AMEN1ALDH1A1TDP1 | |
| SCHEMBL6970288 | 0.85 | ACP3 (0.50) | CES2ACP3IDO1TDO2 | |
| SCHEMBL5185325 | 0.84 | ACP3 (0.54) | POLBMAPTKMT2AMEN1LMNA | |
| SCHEMBL17593410 | 0.82 | CES2 (0.47) | KMT2AMEN1LMNACES2ACP3 | |
| SCHEMBL4749525 | 0.81 | CES2 (0.46) | MAPTKMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL1515694 | 0.78 | ACP3 (0.56) | MAPTKMT2ALMNACES2ACP3 | |
| SCHEMBL11201464 | 0.78 | KMT2A (0.54) | MAOBPOLBMAPTKDM4EKMT2A | |
| SCHEMBL11193839 | 0.78 | ALDH1A1 (0.48) | MAOBPOLBMAPTKMT2AMEN1 | |
| SCHEMBL7555691 | 0.78 | CES2 (0.46) | CES2ACP3IDO1TDO2 | |
| SCHEMBL2010410 | 0.78 | IDO1 (0.47) | MAOBPOLBMAPTKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0099329-A1 | Dithio compounds, pharmaceutical preparations containing them and their use | Zyma SA (CH) | 1984-01-25 | — | — | EP | disclosed |