Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 13/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 10/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 5/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15538502 | 0.84 | ESR1 (0.44) | ESR1ESR2TP53TDP1AR | |
| SCHEMBL7744447 | 0.83 | ESR1 (0.52) | ESR1ESR2TP53TDP1AR | |
| SCHEMBL13703416 | 0.83 | ESR1 (0.48) | ESR1ESR2TP53TDP1TRPA1 | |
| SCHEMBL24191011 | 0.78 | ALDH1A1 (0.53) | ESR1ESR2TDP1ARPDE10A | |
| SCHEMBL217919 | 0.78 | TP53 (0.54) | ESR1ESR2TP53TDP1AR | |
| SCHEMBL30142684 | 0.78 | TP53 (0.54) | ESR1ESR2TP53TDP1AR | |
| SCHEMBL674987 | 0.78 | TP53 (0.54) | ESR1ESR2TP53TDP1AR | |
| SCHEMBL29465801 | 0.78 | TP53 (0.54) | ESR1ESR2TP53TDP1AR | |
| SCHEMBL30343462 | 0.78 | TP53 (0.54) | ESR1ESR2TP53TDP1AR | |
| SCHEMBL22326124 | 0.78 | CYP3A4 (0.45) | ESR1ESR2TP53TDP1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4365098-A | Fluorinated diphenols and method for their preparation | GENERAL ELECTRIC COMPANY (US) | 1982-12-21 | — | — | US | claimed |
| US-12435185-B2 | Method for producing 1,1,1-trifluoro-2,2-bisarylethane, and 1,1,1-trifluoro-2,2-bisarylethane | CENTRAL GLASS COMPANY, LIMITED (JP) | 2025-10-07 | — | — | US | disclosed |
| US-12098238-B2 | Curable resin, curable resin composition, cured product, electronic device, laminated board material, electronic component encapsulant, and method for producing curable resin | CENTRAL GLASS COMPANY, LIMITED (JP) | 2024-09-24 | — | — | US | disclosed |
| EP-4089131-B1 | CURABLE RESIN, CURABLE RESIN COMPOSITION, CURED PRODUCT, ELECTRONIC DEVICE, LAMINATED BOARD MATERIAL, ELECTRONIC COMPONENT ENCAPSULANT, AND METHOD FOR PRODUCING CURABLE RESIN | CENTRAL GLASS CO LTD (JP) | 2024-06-26 | — | — | EP | disclosed |
| US-20230097638-A1 | Curable Resin, Curable Resin Composition, Cured Product, Electronic Device, Laminated Board Material, Electronic Component Encapsulant, and Method for Producing Curable Resin | CENTRAL GLASS COMPANY, LIMITED (JP) | 2023-03-30 | — | — | US | disclosed |
| EP-4089131-A1 | CURABLE RESIN, CURABLE RESIN COMPOSITION, CURED PRODUCT, ELECTRONIC DEVICE, LAMINATED BOARD MATERIAL, ELECTRONIC COMPONENT ENCAPSULANT, AND METHOD FOR PRODUCING CURABLE RESIN | Central Glass Company, Limited (JP) | 2022-11-16 | — | — | EP | disclosed |
| US-20220106444-A1 | Method for Producing 1,1,1-Trifluoro-2,2-Bisarylethane, and 1,1,1-Trifluoro-2,2-Bisarylethane | CENTRAL GLASS COMPANY, LIMITED (JP) | 2022-04-07 | — | — | US | disclosed |
| WO-2020162408-A1 | METHOD FOR PRODUCING 1,1,1-TRIFLUORO-2,2-BISARYLETHANE, AND 1,1,1-TRIFLUORO-2,2-BISARYLETHANE | セントラル硝子株式会社 | 2020-08-13 | — | — | WO | disclosed |
| WO-2020162408-A1 | METHOD FOR PRODUCING 1,1,1-TRIFLUORO-2,2-BISARYLETHANE, AND 1,1,1-TRIFLUORO-2,2-BISARYLETHANE | セントラル硝子株式会社 | 2020-08-13 | — | — | WO | disclosed |
| US-4467121-A | Fluorinated diphenols and method for their preparation | GENERAL ELECTRIC COMPANY (US) | 1984-08-21 | — | — | US | disclosed |
| US-4365098-A | Fluorinated diphenols and method for their preparation | GENERAL ELECTRIC COMPANY (US) | 1982-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220106444-A1 | Method for Producing 1,1,1-Trifluoro-2,2-Bisarylethane, and 1,1,1-Trifluoro-2,2-Bisarylethane | NAF1, FXR1, AFF1 | ESR1 4737/4885ESR2 3744/4885TP53 3544/4885 |
| US-12435185-B2 | Method for producing 1,1,1-trifluoro-2,2-bisarylethane, and 1,1,1-trifluoro-2,2-bisarylethane | NAF1, FXR1, AFF1 | ESR1 4737/4885ESR2 3744/4885TP53 3544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.