Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | CDC25B | P30305 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | OGA | O60502 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11047861 | 0.96 | PTPN1 (0.36) | PTPN1CDC25BL3MBTL1OGA | |
| SCHEMBL11047925 | 0.96 | PTPN1 (0.32) | PTPN1CDC25BOGA | |
| SCHEMBL11049138 | 0.92 | OGA (0.32) | PTPN1CDC25BOGA | |
| SCHEMBL11045989 | 0.88 | OGA (0.33) | PTPN1CDC25BOGA | |
| SCHEMBL11046789 | 0.70 | LMNA (0.39) | OGA | |
| SCHEMBL10441900 | 0.62 | PTPN1 (0.46) | PTPN1CDC25B | |
| SCHEMBL28286060 | 0.61 | TSHR (0.44) | PTPN1CDC25BL3MBTL1 | |
| SCHEMBL10365234 | 0.61 | ENPP2 (0.51) | PTPN1CDC25B | |
| SCHEMBL712254 | 0.59 | TSHR (0.48) | — | |
| SCHEMBL10441639 | 0.59 | ALDH1A1 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482730-A | Synthesis of dioxabicyclo[3.2.1]octanes and oxepanes | ORTHO PHARMACEUTICAL CORPORATION (US) | 1984-11-13 | — | — | US | disclosed |
| US-4387234-A | Synthesis of dioxabicyclo[3.2.1]octanes and oxepanes | ORTHO PHARMACEUTICAL CORPORATION (US) | 1983-06-07 | — | — | US | disclosed |
| US-4322353-A | Synthesis of dioxabicyclo(3.2.1)octanes and oxepanes | ORTHO PHARMACEUTICAL CORPORATION (US) | 1982-03-30 | — | — | US | disclosed |
| EP-0038696-A2 | Synthesis of dioxabicyclo(3.2.1.)octanes and oxepanes | ORTHO PHARMACEUTICAL CORPORATION (US) | 1981-10-28 | — | — | EP | disclosed |