SCHEMBL1105084

SCHEMBL1105084

C1=Cc2c(n(-c3ccccc3)c3ccc(N(c4ccccc4)c4ccc5c(c4)c4ccccc4n5-c4ccccc4)cc23)CC1

nearest known ligand 0.40

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.40
ATM Q13315 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
SIGMAR1 Q99720 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13670888 1.00 KDM4E (0.40) KDM4EATML3MBTL1SIGMAR1
SCHEMBL4403023 0.98 KDM4E (0.38) KDM4EATML3MBTL1
SCHEMBL19071306 0.97 KDM4E (0.38) KDM4EATML3MBTL1
SCHEMBL14051424 0.95 KDM4E (0.38) KDM4EATML3MBTL1
SCHEMBL8956236 0.95 KDM4E (0.38) KDM4EATML3MBTL1
SCHEMBL24611529 0.95 KDM4E (0.38) KDM4EATML3MBTL1
SCHEMBL8956232 0.94 KDM4E (0.37) KDM4EATML3MBTL1
SCHEMBL8950338 0.94 KDM4E (0.37) KDM4EATML3MBTL1
SCHEMBL8950345 0.94 KDM4E (0.37) KDM4EATML3MBTL1
SCHEMBL8956229 0.94 KDM4E (0.37) KDM4EATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090252990-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2009-10-08 US disclosed
US-20090179555-A1 Novel red electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2009-07-16 US disclosed
US-20090153037-A1 Novel red electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2009-06-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090252990-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same AOX1, LEF1, ODC1 KDM4E 2236/4885ATM 4630/4885L3MBTL1 2979/4885
US-20090153037-A1 Novel red electroluminescent compounds and organic electroluminescent device using the same NDUFS2, ALDH1A2, ODC1 KDM4E 1792/4885ATM 4681/4885L3MBTL1 3164/4885
US-20090179555-A1 Novel red electroluminescent compounds and organic electroluminescent device using the same NDUFS2, ALDH1A2, ODC1 KDM4E 1792/4885ATM 4681/4885L3MBTL1 3164/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.