SCHEMBL6570866

SCHEMBL6570866

CCOC(=O)/C=C(/C)NC

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 3/20 0.52
HCAR2 Q8TDS4 1/20 0.43
ALDH1A1 P00352 5/20 0.42
LMNA P02545 3/20 0.42
HSD17B10 Q99714 1/20 0.42
MGAM O43451 1/20 0.41
GAA P10253 1/20 0.41
SI P14410 1/20 0.41
MGAM2 Q2M2H8 1/20 0.41
GLO1 Q04760 1/20 0.38
MAPT P10636 7/20 0.36
KDM4E B2RXH2 3/20 0.36
KMT2A Q03164 2/20 0.36
MEN1 O00255 1/20 0.36
ATM Q13315 1/20 0.36
ALOX15 P16050 1/20 0.36
SOAT1 P35610 1/20 0.36
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24793666 1.00 NPSR1 (0.52) NPSR1HCAR2ALDH1A1LMNAHSD17B10
SCHEMBL1127387 1.00 NPSR1 (0.52) NPSR1HCAR2ALDH1A1LMNAHSD17B10
SCHEMBL30443069 0.89 GAA (0.47) NPSR1HCAR2ALDH1A1LMNAHSD17B10
SCHEMBL11050866 0.84 TSHR (0.37) NPSR1HCAR2ALDH1A1LMNAHSD17B10
SCHEMBL9119949 0.83 HCAR2 (0.47) NPSR1HCAR2ALDH1A1LMNAMAPT
SCHEMBL9119943 0.83 HCAR2 (0.47) NPSR1HCAR2ALDH1A1LMNAMAPT
SCHEMBL11753351 0.81 NPSR1 (0.50) NPSR1HCAR2ALDH1A1LMNAHSD17B10
SCHEMBL5143661 0.81 NPSR1 (0.50) NPSR1HCAR2ALDH1A1LMNAHSD17B10
SCHEMBL19611510 0.81 NPSR1 (0.50) NPSR1HCAR2ALDH1A1LMNAHSD17B10
SCHEMBL10460625 0.81 NPSR1 (0.50) NPSR1HCAR2ALDH1A1LMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111269168-B Preparation method of arbidol intermediate 苏州敬业医药化工有限公司 2022-04-01 CN claimed
CN-109402659-B Green synthesis method of alpha-thioenamine compound 许昌学院 2020-10-20 CN claimed
CN-111269168-A Preparation method of arbidol intermediate 苏州敬业医药化工有限公司 2020-06-12 CN claimed
CN-109402659-A A kind of green synthesis method of α-sulphenamides class compound 许昌学院 2019-03-01 CN claimed
EP-2702035-B1 PROCESS FOR CONTINUOUS FLOW SYNTHESIS OF BETA-AMINO CROTONATE COUNCIL SCIENT IND RES (IN) 2018-03-07 EP claimed
US-20040261198-A1 Restructuring and finishing of keratin fibers HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 2004-12-30 US claimed
US-20250391519-A1 CHEMICAL SYNTHESIS PLATFORM UNIV GLASGOW COURT (GB) 2025-12-25 US disclosed
EP-4548355-A1 CHEMICAL SYNTHESIS PLATFORM The University Court Of The University Of Glasgow (GB) 2025-05-07 EP disclosed
CN-116217461-B Chalcone derivative containing indole structure and preparation method and application thereof 贵州大学 2024-10-18 CN disclosed
WO-2024003151-A1 CHEMICAL SYNTHESIS PLATFORM THE UNIVERSITY COURT OF THE UNIVERSITY OF GLASGOW (GB) 2024-01-04 WO disclosed
CN-116217461-A Chalcone derivative containing indole structure and preparation method and application thereof 贵州大学 2023-06-06 CN disclosed
CN-111269168-B Preparation method of arbidol intermediate 苏州敬业医药化工有限公司 2022-04-01 CN disclosed
CN-109402659-B Green synthesis method of alpha-thioenamine compound 许昌学院 2020-10-20 CN disclosed
US-4284629-A ANIMAL GROWTH REGULATORS BAYER AKTIENGESELLSCHAFT (DE) 1981-08-18 US disclosed
US-4038399-A 1,4-DIHYDROPYRIDINE CARBOXYLIC ACID ESTERS USEFUL AS CORONARY VESSEL DILATORS AND ANTI-HYPERTENSIVES BAYER AKTIENGESELLSCHAFT (DT) 1977-07-26 US disclosed
US-4031104-A ANTIHYPERTENSIVE AGENTS BAYER AKTIENGESELLSCHAFT (DT) 1977-06-21 US disclosed
US-3996234-A CORONARY VESSEL DILATORS, HYPOTENSIVES BAYER AKTIENGESELLSCHAFT (DT) 1976-12-07 US disclosed
US-3974275-A 1,4-Dihydropyridine carboxylic acid esters useful as coronary vessel dilators and anti-hypertensives BAYER AKTIENGESELLSCHAFT (DT) 1976-08-10 US disclosed
US-3933834-A CARDIOVASCULAR AGENTS BAYER AKTIENGESELLSCHAFT (DT) 1976-01-20 US disclosed
US-3932436-A 2-Thiazolone-5-carboxylic acid ester fungicidal agents BAYER AKTIENGESELLSCHAFT (DT) 1976-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250391519-A1 CHEMICAL SYNTHESIS PLATFORM SET, CBS, COASY NPSR1 1827/4885HCAR2 2404/4885ALDH1A1 2847/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.